Name: Miss Kanjana Chaiyot Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3158) E-mail: Position: Research Assistant Research Interests • Molecular and cell signalings Education • B.Sc. Biology, Ramkhamhaeng University Area of expertise • Cell culture, Cytotoxicity testing, Immunoblot analysis Presentations Thiantanawat A,Visitnonthachai D,Chaiyot K, Akanimanee J, Auewarakul C, Satayavivad J. Alterations pf p53, cyclin D1, and apoptotic regulators Bcl-2 and Bax in colorectal cancer tissues. The 7th Princess Chulabhorn International Science Congress (PC VII) “Cancer: From basic research to cure”. November 29-December 3, 2012. Shangri-La Hotel, Bangkok, Thailand. (Poster) Suriyo T,Chaiyot K, Watcharasit P, Thiantanawat A, Satayavivad J. Presence and function role of cholinergic system in cancer. The 7th Princess Chulabhorn International Science Congress (PC VII) “Cancer: From basic research to cure”. November 29-December 3, 2012, Shangri-La Hotel, Bangkok, Thailand. (Poster) Suriyo T,Chaiyot K, Watcharasit P, Thiantanawat A, Satayavivad J. Arsenic alters cholinergic system and dysregulates intracellular calcium in microvascular endothelial HMEC-1 cells. The 8th Congress of Toxicology in Developing Countries (8CTDC), Thai Society of Toxicology under the auspices of the IUTOX “Sharing Toxicological Knowledge for Healthy Life & Environment”, September 10-13, 2012, Bangkok, Thailand. Poster I-14, p. 87. Thiantanawat A, Pianjing P, Visitnonthachai D,Chaiyot K, Watcharasit P, Satayavivad J. Estrogenic...
Name: Miss Jaratluck Akanimanee Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3162) E-mail: Position: Research Scientist Research Interests Pharmaceutical and nutraceutical formulations Education M.Sc. in Pharm. Chulalongkorn University Area of expertise • Screening for antimalarial activity • Pharmaceutical and Nutraceutical formulations Publications Sodium arsenite exposure impairs B cell proliferation and enhances vascular inflammation in Plasmodium berghei mouse model Suntararuks S, Worasuttayangkurn L,Akanimanee J, Suriyo T, Nookabkaew S, ,Srisamut N, Visitnonthachai D, Watcharasit P, Satayavivad J. Environ Toxicol Pharm. 2019; 66: 7-13. In vitroantifungal activities of longan (Dimocarpus longanLour.) seed extract. Rangkadilok N, Tongchusak S, Boonhok R, Chaiyaroj SC, Junyaprasert VB, Buajeeb W,Akanimanee J, Raksasuk T, Suddhasthira T, Satayavivad J. Fitoterapia. 2012; 83:545-53. Conference papers: Akanimanee J, Thiantanawat A, Khamkong P, Rangkadilok, Ritruechai S, Satayavivad J. Effects of Thai’s brown, red, and black rice extracts on in vitro growth of human cancer cell lines. The 7th Princess Chulabhorn International Science Congress (PC VII) “Cancer: From basic research to cure”. November 29-December 3, 2012. Shangri-La Hotel, Bangkok,Thailand. (Poster) Thiantanawat A, Visitnonthachai D, Chaiyot K,Akanimanee J, Auewarakul C, Satayavivad J. Alterations of P53, Cyclin D1and apoptotic regulators BCL2 and BAX in colorectal cancer tissues. The 7th Princess Chulabhorn International Science Congress, Cancer: From basic...
Name: Dr. Jantamas Tuntawiroon Kanitwithayanun Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3167) E-mail: Position: Research Scientist Research Interests • Impact of environmental pollutants and industrial chemicals, particularly carcinogenic compounds on human health through the use of various biological markers • Oxidative stress and inflammation Education • Doctor of Philosophy (Environmental Toxicology, Technology and Management) Inter-university program between Asian Institute of Technology (AIT), Chulabhorn Research Institute (CRI) and Mahidol University (MU), Thailand Area of expertise • Environmental toxicology study, assessment of the possible harmful effects of carcinogenic pollutants on human health Publications • Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells via non-genomic estrogen receptor/ERK1/2 signaling pathway Sritana N, Suriyo T,Kanitwithayanun J, Songvasin BH, Thiantanawat A, Satayavivad J. Food Chem Toxicol. 2018; 118: 595-607. • An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity. Tajai P, Fedeles BI, Suriyo T, Navasumrit P,Kanitwithayanun J, Essigmann JM, Satayavivad J. Free Radic Biol Med. 2018;116: 64-72. • Oxidative DNA damage and inflammatory responses in cultured human cells and in humans exposed to traffic-related particles. Vattanasit U, Navasumrit P, Khadka MB,Kanitwithayanun J, Promvijit J, Autrup H, Ruchirawat M. Int J Hyg...
Name: Dr. Benjaporn Homkajorn Songvasin Office address: Research Laboratory of Pharmacology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 (ext. 3166) Position: Research scientist, Research Laboratory of Pharmacology, Chulabhorn Research Insitute E-mail: [email protected] Research Interests My research focus is on neurobiology study of affecting brain cells both in vitro and in vivo upon the progression of neurodegenerative diseases. I also experienced in development of novel non-viral/antibody based technology for drug and gene delivery into the brain. At Chulabhorn Research Institute, my main research aim is to investigate neuroprotective effects of Thai medicinal plants on acute and chronic brain disorders. Long-term damage of brain cells would possibly lead to the development of neurodegenerative diseases such as stroke, Alzheimer’s and Parkinson’s diseases. An expected outcome to pursue this aim is for the further development of alternative therapy of active compounds deriving from readily available Thai plants. Education and Degrees Doctor of Philosophy; Flinders University, Adelaide, South Australia (July 2008 – December 2011) Master of Biotechnology Studies, upgraded to Ph.D program; Flinders University, Adelaide, South Australia (July 2006 – July 2008) Bachelor of Science (Biotechnology); Mahidol University, Bangkok, Thailand (June 2002 – July 2006) Academic Activities Research scientist Academic Activities Chulabhom Graduate Institue Environmental Toxicology Course: Integrated Life Sciences (0301501): The central nervous system...
Name: Miss Sumitra Suntararuks Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3171) E-mail: Position: Research Scientist I Research Interests • Molecular and cell signaling pathways Education • M.Sc. in Toxicology, Mahidol University • B.Sc. in Nursing, Mahidol University Area of expertise • Lymphocyte proliferation, Immunoblot analysis, RT-PCR technique Awards • The Poster Award Winner on The 8th Congress of Toxicology in Developing Countries (8CTDC) Under the Auspices of International Union of Toxicology (IUTOX) “Sharing Toxicological Knowledge for Healthy Life & Environment” September 10-13, 2012. Centara Grand, Central Ladprao, Bangkok, Thailand. (I-83) p.86. Watcharasit P,Suntararuks S, Visitnonthachai D, Thiantanawat A, Satayavivad J. β-catenin involvement in arsenic-induced VEGF expression in neuroblastoma SH-SY5Y cells • Good Poster Award on The 27th Congress on Science and Technology of Thailand. Prince of Songkla, Hat Yai, Thailand. October 16-18, 2001. p.628. Suriyo T, Tuntawiroon J,Soontararuks S, Satayavivad J. Modification of rotational behavior during subchronic exposure to paraquat in rat Publications •Sodium arsenite exposure impairs B cell proliferation and enhances vascular inflammation in Plasmodium berghei mouse model Suntararuks S, Worasuttayangkurn L, Akanimanee J, Suriyo T, Nookabkaew S, ,Srisamut N, Visitnonthachai D, Watcharasit P, Satayavivad J. Environ Toxicol Pharm. 2019; 66: 7-13. • Arsenic impairs insulin signaling in differentiated...
Name: Miss Sumontha Nookabkaew Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3161) E-mail: Position: Research Scientist I Research Interests • Heavy metals in food, environmental and biological samples, Arsenic speciation Education • Master degree in Applied Analytical and Inorganic Chemistry, Mahidol University • Bachelor degree in Chemistry, Prince of Songkla University Area of expertise • Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Atomic Absorption Spectrometry (AAS), Microwave digestion Publications •Sodium arsenite exposure impairs B cell proliferation and enhances vascular inflammation in Plasmodium berghei mouse model Suntararuks S, Worasuttayangkurn L, Akanimanee J, Suriyo T,Nookabkaew S, ,Srisamut N, Visitnonthachai D, Watcharasit P, Satayavivad J. Environ Toxicol Pharm. 2019; 66: 7-13. • Arsenic speciation and accumulation in selected organs after oral administration of rice extracts in Wistar rats. Lewchalermvong K,Rangkadilok N,Nookabkaew S, Suriyo T, Satayavivad J. J Agric Food Chem. 2018, 66: 3199-3209. • Hijiki and sodium arsenic stimulate growth of human colorectal adenocarcinoma cells through ERK1/2 activation. Cholpraipimorat W, Suriyo T, Rangkadilok N,Nookabkaew S, Satayavivad J. Food Chem Toxicol 2017; 110: 33-41. • Concentrations of trace elements in organic fertilizers and animal manures and feeds and cadmium contamination in herbal tea (Gynostemma pentaphyllum Makino). Nookabkaew S, Rangkadilok N, Prachoom N., Satayavivad J. J Agric...
Name: Mrs. Nanthanit Pholphana Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3164) E-mail: Position: Research Scientist I Research Interests • Bioactive compounds in medicinal plants and foods • Pesticide residues in biological and environmental samples • Pharmacokinetic studies of medicinal plants • Oxidative stress biomarker Education • Master of Science (Microbiology), Faculty of Science, Mahidol University • Bachelor of Science (Health Science, first class honors), Faculty of Science and Technology, Thammasart University Area of expertise • Analytical chemistry (LC-MS/MS, HPLC, Supercritical Fluid Extraction) Publications •Clinical parameters following multiple oral dose administration of a standardizedAndrographis paniculata</> capsule in healthy Thai subjects. Suriyo T,Pholphana N, Ungtrakul T, Rangkadilok N, Panomvana D, Thiantanawat A, Pongpun W, Satayavivad J. Planta Med. 2017;83: 778–789. •Andrographis paniculata: dissolution investigation and pharmacokinetic studies of four major active diterpeniods after multiple oral dose. Pholphana N, Panomvana D, Rangkadilok N, Suriyo T, Puranajoti P, Ungtrakul T, Pongpun W, Thaeopattha S, Songvut P, Satayavivad J. J Ethnopharmacol 194 p513-21 (2016) •A simple and sensitive LC-MS/MS method for determination of four major active diterpenoids fromAndrographis paniculatain human plasma and its application to a pilot study. Pholphana N, Panomvana D, Rangkadilok N, Suriyo T, Ungtrakul T, Pongpun W, Thaeopattha S, Satayavivad J. Planta...
Name: Dr. Tawit Suriyo Office address: Laboratory of Pharmacology, 4th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3159) E-mail: Position: Research Scientist Research Interests • Metals (i.e. mercury, cadmium, arsenic) and pesticides (i.e. paraquat, glyphosate, chlopyrifos) toxicity including immunotoxicity, cardiovascular toxicity, and carcinogenicity • Pharmacology and toxicology of natural products • Neuronal and non-neuronal cholinergic system Education 2009-2010 Post-doctoral Fellow, Center of Excellence on Environmental Health and Toxicology, Commission of Higher Education, Ministry of Education, Thailand 2003-2008 Ph.D. (Environmental Engineering and Management; Environmental Toxicology, Technology and Management), Inter-university program between Asian Institute of Technology (AIT)/ Chulabhorn Research Institute (CRI) and Mahidol University (MU), Thailand 1999-2001 M.Sc. (Toxicology), Mahidol University, Thailand 1995-1998 B.Sc. (Industrial Hygiene and Safety), Burapha University, Thailand Area of expertise •In vitroandin vivostudies • Cell cycle and cell signaling • Flow cytometry-based assay • Gene expression assay • Intracellular calcium assay Award 2015 SOT/AstraZeneca/SOT Endowment Fund / IUTOX Travel Award, International Union of Toxicology (IUTOX) and US Society of Toxicology (SOT), San Diago, USA. “Suriyo T, Tachachartvanich P, Watcharasit, Satayavivad J. Chlorpyrifos promotes the growth of colorectal adenocarcinoma H508 cells through the activation of EGFR/ERK1/2 signaling pathway” ImmunoTools Special Award, ImmunoTools GmbH Company, Germany. “Suriyo T. The immune stimulation and anti-inflammation properties of Thai...
Name: Dr. Piyajit Watcharasit Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3150) E-mail: Position: Research Scientist II Research Interests Neurodegenerative diseases, cell signalings Education Ph.D. (Pharmacology) University of Alabama at Birmingham, Birmingham, Alabama, USA Awards Ph.D. Thesis award (Honorably mentioned) 2003 from National Research Council of Thailand Publications • Sodium arsenite exposure impairs B cell proliferation and enhances vascular inflammation in Plasmodium berghei mouse model Suntararuks S, Worasuttayangkurn L, Akanimanee J, Suriyo T, Nookabkaew S, ,Srisamut N, Visitnonthachai D,Watcharasit P, Satayavivad J. Environ Toxicol Pharm. 2019; 66: 7-13.•Genistein reduces the activation of AKT and EGFR, and the production of IL6 in cholangiocarcinoma cells involving estrogen and estrogen receptors Tanjak P, Thiantanawat A,Watcharasit P, Satayavivad J. Int J Oncol. 2018; 53(1): 177-188.• Arsenic impairs insulin signaling in differentiated neuroblastoma SH-SY5Y cells. Niyomchan A, Visitnonthachai D, Suntararuks S, Ngamsiri P,Watcharasit P, Satayavivad J. NeuroToxicology 2018;66: 22-31.• Paraquat induces extrinsic pathway of apoptosis in A549 cells by induction of DR5 and repression of anti-apoptotic proteins, DDX3 and GSK3 expression. Hathaichoti S, Visitnonthachai D, Ngamsiri P, Niyomchan A, Tsogtbayar O, Wisessaowapak C,Watcharasit P, Satayavivad J. Toxicol in Vitro. 2017;42: 123-129• Perfluorinated chemicals, PFOS and PFOA, enhance the estrogenic effects of 17 β –estradiol in T47D...
Name: Dr. Nuchanart Rangkadilok Office address: Laboratory of Pharmacology, 4thFloor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3157) E-mail: Position: Research Scientist I Research Interests • Plant physiology, Phytochemical analysis, Pharmaceutics and standardization of Thai traditional medicines • Pharmacokinetic of phytochemical compounds in human, Metal analysis in food and its biotransformation Education 1999-2002 Ph.D. (School of Agriculture and Food Systems) The Melbourne School of Land and Environment The University of Melbourne, Australia 1989-1993 Bachelor of Pharmacy (second class honors) Faculty of Pharmacy Chiang Mai University, Chiang Mai, Thailand Area of expertise • Extraction and isolation of phytochemical compounds from medicinal plants • Liquid-liquid and solid phase extraction • TLC, HPLC/GC analysis of phytochemical compounds Publications – Arsenic speciation and accumulation in selected organs after oral administration of rice extracts in Wistar rats. Lewchalermvong K,Rangkadilok N, Nookabkaew S, Suriyo T, Satayavivad J. J Agric Food Chem. 2018, 66: 3199-3209. – The role of nutrition in influencing mechanisms involved in environmentally mediated diseases. Hennig B, Petriello MC, Gamble MV, Surh Y-J, Kresty LA, Frank N,Rangkadilok N, Ruchirawat M, Suk WA. Rev Environ Health. 2018; 33: 87-97 – Clinical parameters following multiple oral dose administration of a standardizedAndrographis paniculatacapsule in healthy Thai subjects. Suriyo T, Pholphana N, Ungtrakul T,Rangkadilok...
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