Name: Assoc. Dr. Oranart Matangkasombut Office address: Laboratory of Biotechnology54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, ThailandTel: +66 25530 8555 (ext. 3251)E-mail: [email protected] Research Scientist Research Experience (Specialties) Molecular biology Education 1988-1994 DDS, Chulalongkorn University 1996-2002 PhD (Biological Sciences in Dental Medicine), Harvard University 2002-2004 Postdoctoral fellowship (with Prof. Gerald R.Fink), Whitehead Institute for Biomedical Research, MA, USA Awards 1995 Anandamahidol scholarship in Dentistry 2002 Harvard School of Dental Medicine Dean’s scholar award Publications– Cefai D., Schneider H., Matangkasombut O., Kang H., Brody J., Rudd C.E. (1998) CD28 receptor endocytosis is targeted by mutations that disrupt phosphatidylinositol 3-kinase binding and costimulation. J Immunol,160(5):2223-30 – Matangkasombut O., Buratowski R.M., Swilling N., Buratowski S. (2000) Bromodomain factor1 corresponds to a missing piece of yeast TFIID. Genes.Dev. 14(8):951-6 – Matangkasombut O., and Buratowski S. (2003) Different sensitivities of bromodomain factors 1 and 2 to histone H4 acetylation. Mol. Cell 11(2):353-63 – Matangkasombut O., Auty R., Buratowski S. (2004) Structure and function of the TFIID complex. Adv Protein Chem. 67:67-92. – Matangkasombut O. (2006) Oral Candidiasis Part I : Clinical Manifestations and Etiology. J Dent Assoc Thai. 56 (1): 52-63 – Matangkasombut O. (2006) Oral Candidiasis Part II : Current therapeutic guidelines. J Dent Assoc Thai. 56 (1): 64-75 – Matangkasombut O., Siraprapa J., and Wongpraparat I. (2006) The development of...
Name: Assoc. Prof. Dr. Rojana Sukchawalit Office address: Laboratory of Biotechnology 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 25530 8555 (ext. 3250) E-mail: [email protected] Research Scientist Research Experience (Specialties) Molecular Microbiology Education 2000-2003 Ph. D. (Biosciences) The University of Birmingham 1993-1996 M. Sc. (Biochemistry) Mahidol University 1990-1993 B. Sc. (Medical Technology) Chulalongkorn University Awards 2012 TRF-CHE-Scopus Young Researcher Award in Life Sciences & Agricultural Sciences Selected Publications Regulation of the Cobalt/Nickel Efflux Operon dmeRF in Agrobacterium tumefaciens and a Link between the Iron-Sensing Regulator RirA and Cobalt/Nickel Resistance. Dokpikul T, Chaoprasid P, Saninjuk K, Sirirakphaisarn S, Johnrod J, Nookabkaew S, Sukchawalit R, Mongkolsuk S. Appl Environ Microbiol. 2016 Jul 15;82(15):4732-42. doi: 10.1128/AEM.01262-16. Agrobacterium tumefaciens Zur Regulates the High-Affinity Zinc Uptake System TroCBA and the Putative Metal Chaperone YciC, along with ZinT and ZnuABC, for Survival under Zinc-Limiting Conditions. Chaoprasid P, Dokpikul T, Johnrod J, Sirirakphaisarn S, Nookabkaew S, Sukchawalit R, Mongkolsuk S. Appl Environ Microbiol. 2016 May 31;82(12):3503-14. doi: 10.1128/AEM.00299-16. Roles of Agrobacterium tumefaciens C58 ZntA and ZntB and the transcriptional regulator ZntR in controlling Cd2+/Zn2+/Co2+ resistance and the peroxide stress response. Chaoprasid P, Nookabkaew S, Sukchawalit R,Mongkolsuk S. Microbiology. 2015 Sep;161(9):1730-40. doi: 10.1099/mic.0.000135. Control of zinc homeostasis in Agrobacterium tumefaciens via zur and the zinc uptake genes znuABC and zinT. Bhubhanil S,...
Name: Dr. James M. Dubbs Office address: Laboratory of Biotechnology 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 25530 8555 (ext. 3250) E-mail: Research Scientist Research Experience (Specialties) 2002-present Research Scientist, Laboratory of Biotechnology, Chulabhorn Research Institute, Lak Si, Bangkok, Thailand — Supervisor: Prof. Skorn Mongkolsuk 1992-2002 Post-Doctoral Research Associate, The Department of Microbiology, The Ohio State University, Columbus, OH, USA 1990-1991 Post-Doctoral Research Assistant, The Department of Biochemistry, Imperial College of Science, Technology and Medicine, London, UK 1985-1990 Graduate Research Assistant, Intercollegiate Program in Genetics, The Pennsylvania State University, University Park, PA, USA 1983-1985 Research Technician, The Department of Molecular and Cellular Biology, The Pennsylvania State University, University Park, PA, USA Education Ph.D. (Genetics) The Pennsylvania State University, University Park, PA, USA,. (December, 1990) B.S. (Microbiology) The Pennsylvania State University, University Park, PA, USA (May, 1983) Training Workshop 1991 Molecular Genetics of Bacillus thuringiensis at Institute of Biological Control, Faculty of Agriculture, Kyushu University, Japan. 1993 Amino acid sequencer and DNA sequencer, Biosystem Japan, Tokyo, Japan 1998 Plant Molecular Genetics, Department of Genetics, Ghent University, Ghent, Belgium. 2000 Bioremediation, AOTS, Yokohama, Japan Publications – Dubbs, J.M. and S. Mongkolsuk. 2012. Peroxide Sensing Transcriptional Regulators in Bacteria. J. Bacteriol. 194(20): 5495-5503.- Sallabhan, R., J. Kerdwong, J. M. Dubbs, K. Somsongkul, W. Whangsuk, P. Piewtongon,...
Name: Dr. Paiboon Vattanaviboon, Ph.D. Office address: Research Laboratory of Biotechnology, Chulabhorn Research Institute 54 Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538377 (office), +66 831790105 (mobile) E-mail: [email protected] Positions: Research Scientist 2, Research Laboratory of Biotechnology, Chulabhorn Research Institute Research Interests Oxidative stress response in pathogenic bacteria Antimicrobial resistance (AMR) mechanisms in bacteria The impact of antibiotic use in agriculture on AMR Education and Degrees: 1979-1983 B.Sc. (Medical Technology, Hons) Mahidol University 1983-1985 M.Sc. (Microbiology) Mahidol University 1996-1999 Ph.D. (Biotechnology) Mahidol University Working Experience 1985-1986: Research Assistant Department of Biotechnology Faculty of Science, Mahidol University 1986-1991: Scientist Department of Microbiology Army Institute of Pathology 1991-present: Research Scientist ...
Previous image Next image CRI’s Institute Animal Care and Use Committee (IACUC) is the oversight body for monitoring and enforcing all animal care and use activities in accordance with CRI’s Animal Care and Use Program (ACUP), policies and standard operating procedures, as well as principles and guidelines in Animals for Scientific Purposes Act, Guide for the Care and Use of Laboratory Animals, 8th ed. (US National Research Council) and the Ethical Principles and Guidelines for the Use of Animals for Scientific Purposes (National Research Council of Thailand). The committee comprises CRI animal researchers, non-laboratory animal researchers, veterinarians, statistician, non-scientists and non-affiliated. New IACUC members must attend a minimum of at least one IACUC training program. All IACUC members are encouraged to attend the aforementioned training once every two years thereafter. Continued IACUC training/updating, in the form of relevant articles and discussions, is conducted during IACUC meetings. The Role of the IACUC include reviews the animal care and use program and conducts animal facility inspections, review animal use protocols and significant changes to the use of animals in ongoing activities, monitor post approval animal protocols and prepare reports to the IO of the IACUC evaluations and recommendations.The IACUC generally meets once a month but no less than once every 6 months. The...
Most antivenoms (AVs) are obtained from the immunization of a large animal (e.g. horse) with only one single venom which resulting to the specific against only a venom, namely monospecific AVs. In case of this AVs, we need to know accurate identification of the culprit snake be bitten. Thus, misdiagnosis could lead to treatment failure and wastage of the expensive AV. To solve this issue, the production of polyspecific antivenom by the immunization with a mixture of venoms from different species of snakes would be useful. Until now, the research on venoms has been continuously developed the efficiency and high dose potency AVs by combination of conventional immunology and advances technology. Therefore, proteomic approach is required for exploration of venom profiles or investigation of the neutralizing toxin by AVs. The challenge of generating effective AVs is universal AV with coverage of all type snakes in a wide geographic area and high efficiency. Furthermore, such AVs would be produced cheaply as a result of economy of scale.
Name: Dr. Thitirat Ngaotepprutaram Office address: Environmental Toxicology Laboratory, Biomedical Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3110) E-mail: Research Scientist Education 1999 – 2003 B.S. (1st Hons) in Genetics, Kasetsart University, Thailand 2003 – 2005 M.Sc. in Molecular Genetics and Genetic Engineering, Mahidol University, Thailand 2006 – 2013 Ph.D. with Dual-Major Program in Pharmacology & Toxicology and Environmental Toxicology, Michigan State University, USA Research Interest/Experiences Immunotoxicity of environmental toxicants Technical expertise includes flow/phosphoflow cytometry, qRT-PCR, gel-shift assay, luciferase reporter assay, ELISA, ELISPOT and mouse and human immune cell isolation and culture. Publications – Ngaotepprutaram T, Kaplan BLF, and Kaminski NE. Suppression by ∆(9)-tetrahydrocannabinol of the primary Immunoglobulin M response by human peripheral blood B cells is associated with impaired STAT3 activation. Toxicology 9;310:84-91, 2013. – Ngaotepprutaram T, Kaplan BLF, and Kaminski NE. Impaired NFAT and NFB activation are involved in auppression of CD40 ligand expression by ∆(9)-tetrahydrocannabinol in human CD4+ T cells. Toxicol Appl Pharmacol. 15;273(1):209-18. – Ngaotepprutaram T, Kaplan BLF, Crawford RB, and Kaminski NE. Differential modulation by delta9-tetrahydrocannabinol (∆9-THC) of CD40 ligand (CD40L) expression in activated mouse splenic CD4+ T cells. J Neuroimmune Pharmacol. 7(4):969-80, 2012 – Kaplan BLF, Lawver JE, Karmaus PW, Ngaotepprutaram T, Birmingham NP, Harkema JR and Kaminski NE. The effects of targeted...
Name: Mister Thundorn Saneanukul Office address: Environmental Toxicology Laboratory, Biomedical Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3179) E-mail: Research Scientist Education Bachelor’s degree in Fisheries from Maejo University Research Interest I have been working in the Aquatic Toxicity Testing Unit (ATTU), where, part of the Environmental Toxicology Laboratory. ATTU could be set up to run Whole Effluent Toxicity (WET) tests. This project is part of Tetra Tech’s development of a code of Practice for produced water in the Gulf of Thailand.
Name: Mister Samroeng Chantchaemsai Office address: Environmental Toxicology Laboratory, Biomedical Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3106-7) E-mail: [email protected] Research Assistant Education B.Sc (Agricultural extension and communication) LL.B (Law) B.Pol.Sc. (Comparative politics and international relations) Research Interest PAHs in ambient air/ 10 years Benzene, 1,3-butadien in ambient air/ 8 years Biofuel emission from automotive/2 years E-Waste /current work Publications Potential health effects of exposure to carcinogenic compounds in incense smoke in temple workers. Navasumrit P, Arayasiri M, Hiang OM, Leechawengwongs M, Promvijit J, Choonvisase S, Chantchaemsai S, Nakngam N, Mahidol C, Ruchirawat M Chem Biol Interact173p19-31(2008 May 9)
Name: Miss Somchamai Waraprasit Office address: Environmental Toxicology Laboratory, Biomedical Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3110) E-mail: [email protected] Research Scientist Education 2006 Bachelor of Science (Biology, 1st class honor) Kasetsart University (KU) 2009 Master of Science (Environmental Toxicology) Chulabhorn Graduate Institute (CGI) Research Experiences DNA damage determination by Comet assay Gene expression by real time RT-PCR DNA methylation analysis by Pyrosequencing and COBRA Publications Effects of arsenic exposure on DNA methylation in cord blood samples from newborn babies and in a human lymphoblast cell line. Intarasunanont P, Navasumrit P, Waraprasit S, Chaisatra K, Suk WA, Mahidol C, Ruchirawat M Environ Health11p31(2012 May 2)
Name: Miss Varabhorn Parnlob Office address: Environmental Toxicology Laboratory, Biomedical Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3110) E-mail: [email protected] Research Scientist Education Bachelor of Science (Environmental Science and Technology),Mahidol University Master of Science (Toxicology), Mahidol University Research Interest/Experiences – Oxidative damage – Base Excision Repair Publications Environmental and occupational exposure to benzene in Thailand. Navasumrit P, Chanvaivit S, Intarasunanont P, Arayasiri M, Lauhareungpanya N, Parnlob V, Settachan D, Ruchirawat M Chem Biol Interact153-154p75-83(2005 May 30) Low level occupational exposure to styrene: Its effects on DNA damage and DNA repair. Wongvijitsuk S, Navasumrit P, Vattanasit U, Parnlob V, Ruchirawat M Int J Hyg Environ Healthp(2010 Oct 26)
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