Name: Dr. Siriporn Keeratichamroen Office address: B705C, 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3239) E-mail: [email protected] Research Scientist I Research Interests Cancer Biology, Cell Signaling, Cancer Microenvironment Education – B. Sc. Chemistry – Kasetsart University, Bangkok, Thailand – M. Sc. Molecular Genetics and Genetic Engineering – Mahidol University, Bangkok, Thailand – Ph. D. Molecular Medicine – Mahidol University, Bangkok, Thailand Publications 1. Thongnest S, Boonsombat J, Keeratichamroen S, Lirdprapamongkol K, Kaweetripob W, Kheawchaum S, Mahidol C, Svasti J, Ruchirawat S, Prawat H. Acetogenins from the stems of Uvaria micrantha showing antiproliferative effects on HepG2 liver cancer cells. Phytochemistry. 2022 Sep 24;204:113450. doi: 10.1016/j.phytochem.2022.113450. Epub ahead of print. PMID: 36162462. 2. Keeratichamroen S, Lirdprapamongkol K, Thongnest S, Boonsombat J, Chawengrum P, Sornprachum T, Sirirak J, Verathamjamras C, Ornnork N, Ruchirawat S, Svasti J. JAK2/STAT3‑mediated dose‑dependent cytostatic and cytotoxic effects of sesquiterpene lactones from <i>Gymnanthemum extensum</i> on A549 human lung carcinoma cells. Oncol Rep. 2022 Jan;47(1):6. doi: 10.3892/or.2021.8217. Epub 2021 Nov 5. PMID: 34738622; PMCID: PMC8600427. 3. Keeratichamroen S, Subhasitanont P, Chokchaichamnankit D, Weeraphan C, Saharat K, Sritana N, Kantathavorn N, Wiriyaukaradecha K, Sricharunrat T, Paricharttanakul NM, Auewarakul C, Svasti J, Srisomsap C. Identification of potential cervical cancer serum biomarkers in Thai patients. Oncol Lett. 2020...

Name: Dr. Sasivimon Pramual Office address: B704A, 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3232) Mobile: +66 8 9120 6267 E-mail: [email protected] Research Scientist Research Interests Nanoparticle-based drug delivery, Cancer biology Education – Ph.D. (Biotechnology), Mahidol University, Thailand – M.Sc. (Biotechnology), Mahidol University, Thailand – B.Sc. (Biology), Kasetsart University, Thailand Publications 1. Pramual S, Lirdprapamongkol K, Jouan-Hureaux, Barberi-Heyob M, Frochot C, Svasti J, Niamsiri N. Overcoming the diverse mechanisms of multidrug resistance in lung cancer cells by photodynamic therapy using pTHPP-loaded PLGA-lipid hybrid nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics. 2020;149:218-28. 2. Pramual S, Lirdprapamongkol K, Svasti J, Bergkvist M, Jouan-Hureaux V, Arnoux P, Frochot C, Barberi-Heyob M, Niamsiri N. Polymer-lipid-PEG hybrid nanoparticles as photosensitizer carrier for photodynamic therapy. Journal of Photochemistry and Photobiology B: Biology. 2017;173:12-22. 3. Pramual S, Assavanig A, Bergkvist M, Batt CA, Sunintaboon P, Lirdprapamongkol K, Svasti J, Niamsiri N. Development and characterization of bio-derived polyhydroxyalkanoate nanoparticles as a delivery system for hydrophobic photodynamic therapy agents. Journal of Materials Science: Materials in Medicine. 2016;27(2):40.

Name: Mister Phreeranat Montatip Office address: B704A, 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. -) Mobile: +66-61-807-6667 E-mail: [email protected] Research Assistant Research Interests Cancer biology, Cell cycle, Cell death, Signaling and Mechanism, Bioactive compound. Education – B.Sc. (Biotechnology), Chiang Mai University, THAILAND Publications 1. Chaiputtanapun, P., Lirdprapamongkol, K., Thanaussavadate, B., Phongphankhum, T., Thippong, T., Thangsan, P., Montatip, P., Ngiwsara, L., Svasti, J., Chuawong, P. (2022). Biphasic dose‐dependent G0/G1 and G2/M cell cycle arrest by synthetic 2, 3‐arylpyridylindole derivatives in A549 lung cancer cells. Chem Med Chem. 2022;17(14):e202200127.

Name: Miss Phichamon Phetchahwang Office address: B704A, 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. -) Mobile: +66-62-227-6347 E-mail: [email protected] Research Scientist Research Interests Cancer biology, Cancer stem-like cell, Cholangiocarcinoma, Cell death, Signaling and Mechanism, Alternative splicing. Education – B.Sc. (Biotechnology), Naresuan University, THAILAND – M.Sc. (Biochemistry), Naresuan University, THAILAND Publications 1. Tangwiriyarotkul, P., Phetchahwang, P., Krobthong, S., Roytrakul, S., Wongkham, S., & Kaewkong, W. (2019). AB034. P-02. Depletion of SRSF1 inhibits proliferation, promotes apoptosis and changes cellular proteome of cholangiocarcinoma cells. Hepatobiliary Surgery and Nutrition, 8(Suppl 1), AB034. 2. Phetchahwang, P., & Kaewkong, W. (2020). Elevating the Autophagic Process by Balancing the Biological Clock. Srinagarind Medical Journal, 35(3), 340-345.

Name: Miss Phannee Sawangareetrakul Office address: Laboratory of Biochemistry 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3238) E-mail: [email protected] Research Scientist I Research Interests Protein and enzyme, Cancer biomarker, Human genetic disease Education – B.Sc. (Medical Technology), Mahidol University, Bangkok, THAILAND – M.Sc. (Biochemistry), Mahidol University, Bangkok, THAILAND Publications 1. Ngiwsara L, Sawangareetrakul P, Wattanasirichaigoon D, Tim-Aroon T, Dejkhamron P, Champattanachai V, Ketudat-Cairns JR, Svasti J. Effects of gentamicin inducing readthrough premature stop Codons: A study of alpha-L-iduronidase nonsense variants in COS-7 Cells. Biochem Biophys Res Commun. 2022 Oct 27;636(Pt 1):147-154. doi: 10.1016/j.bbrc.2022.10.081. 2. Gorantla JN, Maniganda S, Pengthaisong S, Ngiwsara L, Sawangareetrakul P, Chokchaisiri S, Kittakoop P, Svasti J, Ketudat Cairns JR. Chemoenzymatic and Protecting-Group-Free Synthesis of 1,4-Substituted 1,2,3-Triazole-α-d-glucosides with Potent Inhibitory Activity toward Lysosomal α-Glucosidase. ACS Omega. 2021 Sep 22;6(39):25710-25719. doi: 10.1021/acsomega.1c03928. 3. Sawangareetrakul P, Ngiwsara L, Champattanachai V, Chokchaichamnankit D, Saharat K, Ketudat Cairns JR, Srisomsap C, Khwanraj K, Dharmasaroja P, Pulkes T, Svasti J. Aberrant proteins expressed in skin fibroblasts of Parkinson’s disease patients carrying heterozygous variants of glucocerebrosidase and parkin genes. Biomed Rep. 2021 Apr;14(4):36. doi: 10.3892/br.2021.1412. Epub 2021 Feb 17. 4. Ngiwsara L, Vatanavicharn N, Sawangareetrakul P, Liammongkolkul S, Ratanarak P, Boonyawat B, Srisomsap C, Champattanachai V, Ketudat-Cairns J,...

Name: Mrs. Papada Chaisuriya Office address: Laboratory of Biochemistry, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3235) E-mail: [email protected] Research Assistant Education B.Sc. Biology Srinakarinwirot University, Bangsan Campus, Thailand Publications 1. Komkleow S, Weeraphan C, Chokchaichamnankit D, Chaisuriya P, Verathamjamras C, Ruangjaroon T, Svasti J, Sangvanich P, Srisomsap C*. Global Analysis of Protein Expression in A549 Cells After Prolonged Nicotine Exposure by Using Label-free Quantification. Anticancer Res. 2021;41(8):3833-42. 2. Aroonvilairat S, Tangjarukij C, Sornprachum T, Chaisuriya P, Siwadune T, Ratanabanangkoon K*. Effects of topical exposure to a mixture of chlorpyrifos, cypermethrin and captan on the hematological and immunological systems in male Wistar rats. Environ Toxicol Pharmacol. 2018;59:53-60. 3. Sintiprungrat K, Watcharathanyachat T, Senevirathne W, Chaisuriya P, Chokchaichamnankit D, Srisomsap C, Ratanabanangkoon K*. A comparative study of venomics of Naja naja from India and Sri Lanka, clinical manifestations and antivenomics of an Indian polyspecific antivenom. . 2016;132:131-43. 4. Intaramat A, Sornprachum T, Chantrathonkul B, Chaisuriya P, Jongruja N, Kumsang Y, Sandee A, Santurio J, Grooters A, Ratanabanangkoon K. Protein A/G-based immunochromatographic test for serodiagnosis of pythiosis in human and animal subjects from Asia and Americas. Med Mycol. 2016;54(6):641-7. 5. Sintiprungrat K, Chaisuriya P, Watcharathanyachat T, Ratanabanangkoon K*. Immunoaffinity chromatography in antivenomics studies: Various parameters that can affect the...

Name: Dr. Chantragan Srisomsap Phiphobmongkol Office address: Laboratory of Biochemistry, Chulabhorn Research Institute,54 Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand. Tel: +66 2553 8679 E-mail: [email protected] Associate Vice President for Research Research Scientist II Research Interests Cancer proteomics research including biomarkers and anticancer drugs treatment on cancer cell lines. Protein and enzyme changes in relation to human cancer, genetic diseases including abnormal hemoglobins and inborn errors of metabolism; carbohydrate-modifying enzymes. Plant proteomics. Foodomics, Biological impacts of pesticides. Education 1978 B.Sc. (Chemistry), Kasetsart University, Bangkok 1987 Ph.D. (Biochemistry), Auburn University, Alabama 36830, U.S.A. 1986-1989 Postdoctoral Fellow with 3 publications, Cell Biology and Anatomy Department, University of Alabama at Birmingham, Alabama 35249, U.S.A. Publications: about 100 papers from year 1986-present 1. Srisomsap C., Sawangareetrakul P., Subhasitanont P., Chokchaichamnankit D., Chiablaem K., Bhudhisawasdi V., Wongkham S. and Svasti J. Proteomic Studies of Cholangiocarcinoma and Hepatocellular carcinoma Cell Secretomes. J Biomedicine and Biotechnology, 2010, Article ID 437143, 18 pages. 2. Peng L., Kapp E.A., Fenyö D., Kwon M.S., Jiang P., Wu S., Jiang Y., Aguilar M.I., Ahmed N., Baker M.S., Cai Z., Chen Y.J., Van Chi P., Chung M.C., He F., Len A.C., Liao P.C., Nakamura K., Ngai S.M., Paik Y.K., Pan T.L., Poon T.C., Hosseini Salekdeh G., Simpson R.J., Sirdeshmukh R., Srisomsap C., Svasti J., Tyan Y.C., Dreyer F.S.,...

Name: Miss Pantipa Subhasitanont Office address: B704B, 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3241) E-mail: [email protected] Research Scientist Education – B.Sc. (Biotechnology) Mahidol University, Bangkok, Thailand – M.Sc. (Biochemistry) Mahidol University, Bangkok, Thailand Publications 1. Keeratichamroen S, Subhasitanont P, Chokchaichamnankit D, Weeraphan C, Saharat K, Sritana N, Kantathavorn N, Wiriyaukaradecha K, Sricharunrat T, Paricharttanakul NM, Auewarakul C, Svasti J, Srisomsap C. Identification of potential cervical cancer serum biomarkers in Thai patients. Oncol Lett. 2020; 19(6): 3815-3826. 2. Chokchaichamnankit D, Watcharatanyatip K, Subhasitanont P, Weeraphan C, Keeratichamroen S, Sritana N, Kantathavorn N, Diskul-Na-Ayudthaya P, Saharat K, Chantaraamporn J, Verathamjamras C, Phoolcharoen N, Wiriyaukaradecha K, Paricharttanakul NM, Udomchaiprasertkul W, Sricharunrat T, Auewarakul C, Svasti J, Srisomsap C. Urinary biomarkers for the diagnosis of cervical cancer by quantitative label-free mass spectrometry analysis. Oncol Lett. 2019; 17(6): 5453-5468. 3. Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Keeratichamroen S, Ngiwsara L, Paricharttanakul NM, Lirdprapamongkol K, Weeraphan C, Svasti J, Srisomsap C. Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells. Oncol Lett. 2017; 14(4): 4361-4371. 4. Verathamjamras C, Weeraphan C, Chokchaichamnankit D, Watcharatanyatip K, Subhasitanont P, Diskul-Na-Ayudthaya P, Mingkwan K, Luevisadpaibul V, Chutipongtanate S, Champattanachai V, Svasti J, Srisomsap C. Secretomic profiling of cells from hollow fiber bioreactor reveals...

Name: Narittira Ornnork Office address: B704A, 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 8349) Mobile: 0982716213 E-mail: [email protected] Research Assistant Research Interests Cancer biology, Cell signaling, Drug resistance, Drug discovery, Apoptosis Education – B.Sc. (Biotechnology), King Mongkut’s University of Technology North Bangkok, THAILAND Publications 1. Ornnork, N., Kiriwan, D., Lirdprapamongkol, K., Choowongkomon, K., Svasti, J., & Eurtivong, C. (2020). Molecular dynamics, MM/PBSA and in vitro validation of a novel quinazoline-based EGFR tyrosine kinase inhibitor identified using structure-based in silico screening. Journal of Molecular Graphics and Modelling, 99, 107639. 2. Saruengkhanphasit, R., Butkinaree, C., Ornnork, N., Lirdprapamongkol, K., Niwetmarin, W., Svasti, J., & Eurtivong, C. (2021). Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure–activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study. Bioorganic Chemistry, 110, 104795. 3. Keeratichamroen, S., Lirdprapamongkol, K., Thongnest, S., Boonsombat, J., Chawengrum, P., Sornprachum, Ornnork, N., & Svasti, J. (2022). JAK2/STAT3‑mediated dose‑dependent cytostatic and cytotoxic effects of sesquiterpene lactones from Gymnanthemum extensum on A549 human lung carcinoma cells. Oncology Reports, 47(1), 1-11.

Name: Dr. Lukana Ngiwsara Office address: B701C, 7th Floor, Biomedical Science Building 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3237-8) E-mail: [email protected] Position Research Scientist I Research interests Human genetic disease Cancer biology Education – B.Sc. (Biochemistry), Chulalongkorn University, Thailand – M.S. (Biochemistry), Mahidol University, Thailand – M.S. (Agrobiology), Hokkaido University, Japan – Ph.D. (Agrobiology), Hokkaido University, Japan Scholarships 2000-2002 Royal Golden Jubilee (Chulabhorn foundation) 2007-2012 Japanese Government Scholarship (MEXT) Publications – Anurathapan U, Tim-Aroon T, Zhang W, Sanpote W, Wongrungsri S, Khunin N, Chutipongtanate S, Chirdkiatgumchai V, Ngiwsara L, Jaovisidha S, Khongkraparn A, Pakakasama S, Svasti J, Setchell KDR, Wattanasirichaigoon D, Hongeng S. Comprehensive and long-term outcomes of enzyme replacement therapy followed by stem cell transplantation in children with Gaucher disease type 1 and 3. Pediatr Blood Cancer. 2023 Mar;70(3):e30149. doi: 10.1002/pbc.30149. Epub 2022 Dec 23. – Ngiwsara L, Sawangareetrakul P, Wattanasirichaigoon D, Tim-Aroon T, Dejkhamron P, Champattanachai V, Ketudat-Cairns JR, Svasti J. Effects of gentamicin inducing readthrough premature stop Codons: A study of alpha-L-iduronidase nonsense variants in COS-7 Cells. Biochem Biophys Res Commun. 2022 Oct 27;636(Pt 1):147-154. doi: 10.1016/j.bbrc.2022.10.081. – Chaiputtanapun P, Lirdprapamongkol K, Thanaussavadate B, Phongphankhum T, Thippong T, Thangsan P, Montatip P, Ngiwsara L, Svasti J, Chuawong P. Biphasic Dose-Dependent G0/G1 and G2/M Cell-Cycle Arrest by...

Name: Dr. Kriengsak Lirdprapamongkol Office address: Laboratory of Biochemistry, 7th floor, Biomedical Science Building Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 2553 8555 (ext. 3239) Mobile: +66-86-986-4485 Fax: +66-2-553-8572 E-mail: [email protected] Research Scientist II Research Interests Cancer biology, Metastasis, Drug resistance, Hypoxia, Apoptosis, Cell signaling, Drug discovery, Photodynamic therapy, Sonodynamic therapy, Natural products Education – B.Sc. (Biotechnology), King Mongkut’s Institute of Technology Ladkrabang, THAILAND – M.Sc. (Biochemistry), Mahidol University, THAILAND – Ph.D. (Biochemistry), Mahidol University, THAILAND Publications Journal 1. Thongnest S, Boonsombat J, Keeratichamroen S, Lirdprapamongkol K, Kaweetripob W, Kheawchaum S, et al. Acetogenins from the stems of Uvaria micrantha showing antiproliferative effects on HepG2 liver cancer cells. Phytochemistry. 2022;204:113450. 2. Keeratichamroen S, Lirdprapamongkol K, Thongnest S, Boonsombat J, Chawengrum P, Sornprachum T, et al. JAK2/STAT3mediated dosedependent cytostatic and cytotoxic effects of sesquiterpene lactones from Gymnanthemum extensum on A549 human lung carcinoma cells. Oncol Rep. 2022;47(1). 3. Chaiputtanapun P, Lirdprapamongkol K, Thanaussavadate B, Phongphankhum T, Thippong T, Thangsan P, et al. Biphasic Dose-Dependent G0/G1 and G2/M Cell-Cycle Arrest by Synthetic 2,3-Arylpyridylindole Derivatives in A549 Lung Cancer Cells. ChemMedChem. 2022;17(14):e202200127. 4. Saruengkhanphasit R, Butkinaree C, Ornnork N, Lirdprapamongkol K, Niwetmarin W, Svasti J, et al. Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure-activity relationships as potent tubulin inhibitors and anticancer agents:...

Name: Miss Daranee Chokchaichamnankit Office address: B704B, 7th Floor, Biomedical Science Building, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +66 25530 8555 (ext. 3235, 8530) E-mail: [email protected] Research Scientist Research Interests Protein purification and protein assay, Cancer proteomics Education B.Sc. Chemistry, Ramkhamhaeng University, Bangkok, THAILAND M.Sc. Chemistry, Kasetsart University, Bangkok, THAILAND Publications 1. Nonthawong K., Srisomsap C., Chokchaichamnankit D., Svasti J., Phiriyangkul P. Comparative proteomics and in silico allergenicity of fresh and powdered skipjack tuna and Nile tilapia. Food Control. Volume 144, February 2023, 109345. https://doi.org/10.1016/j.foodcont.2022.109345 2. Watcharatanyatip K., Chutipongtanate S., Chokchaichamnankit D., Weeraphan C., Mingkwan K., Luevisadpibul V., Newburg D.S., Morrow A.L., Svasti J. and Srisomsap C. Translational Proteomic Approach for Cholangiocarcinoma Biomarker Discovery, Validation, and Multiplex Assay Development: A Pilot Study. Molecules. 27(18): 5904, 2022. https://doi.org/10.3390/molecules27185904 3. Komkleow S., Weeraphan C., Chokchaichamnankit D., Chaisuriya P., Verathamjamras C., Ruangjaroon T., Svasti J., Sangvanich P. and Srisomsap C. Global Analysis of Protein Expression in A549 Cells After Prolonged Nicotine Exposure by Using Label-free Quantification. Anticancer Res. 41(8):3833-3842, 2021. doi: 10.21873/anticanres. 15176. PMID: 34281843 4. Mon M.M., Srisomsap C., Chokchaichamnankit D., Watcharatanyatip K., Weeraphan C., Svasti J., Maneechai K., Thongsuksai P. and Raungrat P. Expressed IGHG3 and A1AG1 as Potential Predictors of Chemotherapeutic Response in Advanced Non-small Cell Lung Cancer. Anticancer Res. 41(4):1871-1882, 2021. doi:...