Name: Dr. Charlermchai Artpradit Office address: Research Laboratory of Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 (office), +6683-6198686 (mobile) Position: Research Scientist I, Research Laboratory of Translational Research Unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests Biologics drug discovery: Design and screen for lead compound using as a therapeutic drug or vaccine development using bacterial, insect-baculovirus expression system and mammalian expression system (HEK- 293 and CHO cell). Cell line and process development: Performed cell line development for leads candidate of biosimilars as well as new biologics especially for monoclonal antibody. Small scale process optimization using both conventional cell culture as well high throughput robotic screening. During the optimization both single-use technology as well as conventional re-use system were utilized. Process scale-up for fed-batch and perfusion process using stirred-tank bioreactor as well as rocking bioreactor. Drug quality control: Set up and optimization for biologics characterization including ELISA for quantitation and binding assay, cell-based assay, CEX-HPLC, SEC-HPLC for impurity determination as well as for quantitation, titer measurement using Octet, Western-blot, transmission electron microscope, MALDI-TOF etc. Virology work: Propagate virus under BSL-2 condition and perform related testing using virus as a test system for biologics efficacy or production inoculum. Process development and process scale-up: Set-up and optimization for process scale-up...

Name: Dr. Patchara Ngok-ngam Office address: Research Laboratory of Translational Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 (office), +66869868418 (mobile) Position: Research scientist Research Laboratory of Translational Unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests 1. Nonclinical study of biologics (pharmacokinetics, pharmacodynamics, toxicology) 2. Monoclonal antibody production using hybridoma for detection kit and drug development 3. Anti-drug antibody (ADA) determination, ADA detection method development and validation, ADA detection kit development Education and Degrees • Chiang-Mai University, 2003-2006 – B.Sc. Associated Medical Sciences (Medical Technology), • Mahidol University, 2007-2009 – M.Sc. Biotechnology • Chulabhorn Graduate Institute, 2010-2015 – Ph.D. Applied Biological Science Program Professional Societies • Member: The Association of Medical Technologists of Thailand ( 6765), 2010-present Publications A.Research Articles in International Journals 1. Ngok-Ngam, P., Watcharasit, P., Thiantanawat, A., & Satayavivad, J. (2013). Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells. Cellular & molecular biology letters, 18(1), 58–74. https://doi.org/10.2478/s11658-012-0039-y] 2. Bhubhanil, S., Ruangkiattikul, N., Niamyim, P., Chamsing, J., Ngok-Ngam, P., Sukchawalit, R., & Mongkolsuk, S. (2012). Identification of amino acid residues important for the function of Agrobacterium tumefaciens Irr protein. FEMS microbiology letters, 335(1), 68–77. https://doi.org/10.1111/j.1574-6968.2012.02638.x 3. Ngok-Ngam, P., Ruangkiattikul, N., Mahavihakanont, A., Virgem, S. S.,...

Name : Dr. Phanthakarn Tit-oon, PhD Office address: Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-554-1900 ext. 2617 (office) E-mail: [email protected] Position: Research Scientist, Translational Research Unit, Chulabhorn Research Institute Research Interests: 1. Biopharmaceuticals 2. Research and development 3. Cell-based and ligand binding assays Education and Degrees PhD (Applied Biological Sciences: Environmental Health), Chulabhorn Graduate Institute, Bangkok, Thailand, 2014. MSc (Biochemistry), Mahidol University, Bangkok, Thailand, 2008. BSc (Medical Technology), Chiang Mai University, Chiang Mai, Thailand, 2004. Academic and Research Positions Research Scientist (2018-Present), Translational Research Unit, Chulabhorn Research Institute, Bangkok, Thailand. Postdoctoral Associate (2017-2018), David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, United States. Researcher (2015-2016), Siriraj Metabolomics and Phenomics Center, Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand. Lecturer (2008-2009), Department of Clinical Chemistry, Faculty of Medical Technology, Huachiew Chalermprakiet University, Samutprakan, Thailand. Professional Societies Member: Protein Society of Thailand, 2022-present. Member: The Association of Medical Technologist of Thailand, 2017-present. International Awards & Honours The best poster presentation award (honorable mention) at the 17th International Symposium of the Protein Society of Thailand (PST). Chiang Mai, Thailand. November 2022. The travel award for young investigators at the 12th Human Proteome Organization (HUPO) World Congress. Yokohama, Japan. September 2013. The outstanding abstract award at...

Name: Dr. Amnart Khongmanee Office address: Translational Research Unit, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5541900 ext.2620 (office) Positions: Research Scientist, Translational Research Unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests 1. Biotherapeutic protein characterization 2. Mass spectrometry 3. Proteomics Education and Degrees: • PhD (Applied Biological Sciences: Environmental Health), Chulabhorn Graduate Institute, Bangkok, Thailand, 2014. • MSc (Biochemistry), Mahidol University, Bangkok, Thailand, 2009. • BSc (Medical Technology), Walailak University, Nakhon Si Thammarat, Thailand, 2005. Academic Positions • Research Scientist (2014-Present), Translational Research Unit, Chulabhorn Research Institute, Bangkok, Thailand. • Postdoctoral Associate (2016-2018), David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Massachusetts, United States. Professional Societies • Member: Protein Society of Thailand, 2022-present. ORCID iD: https://orcid.org/0000-0002-9821-1169 Publications 1. Chantaraamporn J, Champattanachai V, Khongmanee A, Verathamjamras C, Prasongsook N, Mingkwan K, et al. Glycoproteomic Analysis Reveals Aberrant Expression of Complement C9 and Fibronectin in the Plasma of Patients with Colorectal Cancer. Proteomes. 2020;8(3). 2. Khongmanee A, Lirdprapamongkol K, Tit-oon P, Chokchaichamnankit D, Svasti J, Srisomsap C. Proteomic analysis reveals important role of 14-3-3sigma in anoikis resistance of cholangiocarcinoma cells. Proteomics. 2013;13(21):3157-66. 3. Sirivatanauksorn Y, Sirivatanauksorn V, Srisawat C, Khongmanee A, Tongkham C. Differential expression of sprouty genes in hepatocellular carcinoma. J Surg Oncol. 2012;105(3):273-6. 4. Tit-Oon P,...

Name: Miss Thanutsorn Susantad, Ph.D. Office address: Research Laboratory of Translational Research Unit87, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand Tel: +662-5538555 ext. 3211 (office), +6689-1699161 (mobile) Position: Researcher, Research Laboratory of Translational Research Unit, Chulabhorn Research Institute E-mail: [email protected] Research Interests 1. Biosimilar 2. Biobetter 3. Bioassays Education and Degrees: • B.Sc. (First Class Honors) in Biotechnology, King Mongkut’s Institute of Technology Ladkrabang (KMITL), Thailand, 2001-2004 • M.Sc. (Dean’s list) in Molecular Genetics and Genetic Engineering, Institute of Molecular Biosciences, Mahidol University, Thailand, 2005-2008 • Ph.D. in Environmental Toxicology, Chulabhorn Graduate Institute (CGI), Thailand, 2012-2018 Academic Activities (If any) Local Activities • Vice President, CGI Student Union, 2012-2013 Fellowships • Visiting Graduate Student, Massachusetts Institute of Technology (MIT), U.S., 2015-2016 Local Awards & Honours • Outstanding B.Sc Undergraduate Student, Faculty of Science, King Mongkut’s Institute of Technology Ladkrabang, Thailand, 2004 • Outstanding B.Sc Graduate Student, Professor Dr.Tab Nilanidhi Foundation, Chulalongkorn University, Thailand, 2005 • Research Assistantship, Faculty of Graduate Studies, Mahidol University, Thailand, 2007 • Outstanding M.Sc Graduate Student, Professor Dr.Tab Nilanidhi Foundation, Chulalongkorn University, Thailand, 2008 • DEAN’S LIST Award, Faculty of Graduate Studies, Mahidol University, Thailand, 2009 • Outstanding Employee, National Science and Technology Development Agency (NSTDA), Ministry of Science and Technology, Thailand, 2009 • Ph.D. (Doctorate) Scholarship, Chulabhorn...