Integrated transcriptomics and network analysis identified altered neural mechanisms in frontal aging brain‑associated Alzheimer’s disease

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An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity. Tajai, P., Fedeles, B. I., Suriyo, T., Navasumrit, P., Kanitwithayanun, J., Essigmann, J. M., &Satayavivad, J. (2018). Free Radical Biology and Medicine, 116, 64-72.