Dr. Phanruethai Pailee

Name : Dr. Phanruethai Pailee (Research Scientist I)
Office Address : Room : R503 / R512
Laboratory of Natural Products
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel : +66 2553 8555 (ext. 3061-2, 3074)
Email : [email protected]

Research Interests
Isolation and Purification of Compounds from Natural Products by Chromatographic Techniques.
Structure Elucidation of Pure Compounds from Natural Products by Spectroscopic Techniques.
Studies of Chemopreventive and Chemotherapeutic Activities of Pure Compounds from Natural Products.

Education
1998-2006 Ph.D Chemistry, Mahidol University, Bangkok, Thailand
1994-1998 B.Sc. Chemistry, Kasetsart University, Bangkok, Thailand

Work Experiences
2006 – present Research Scientist, Chulabhorn Research Institute, Thailand

Publications
Selected Publications

1. Pailee, P.; Prawat, H.; Ploypradith, P.; Mahidol, C.; Ruchirawat, S.; Prachyawarakorn, V. Atalantiaphyllines A-G; Prenylated Acridones from Atalantia monophylla and Their Aromatase Inhibition and Cytotoxic Activities. Phytochemistry 2020, 180, 112525.
2. Pailee, P.; Mahidol, C.; Ruchirawat, S.; Prachyawarakorn, V. Diverse Flavonoids from the Roots of Millettia brandisiana. Phytochemistry 2019, 162, 157-164.
3. Pailee, P.; Mahidol, C.; Ruchirawat, S.; Prachyawarakorn, V. Sterols from Thai Marine Sponge Petrosia (Strongylophora) sp. and Their Cytotoxicity. Mar. Drugs 2017, 15, 54.
4. Pailee, P.; Sangpetsiripan, S.; Mahidol, C.; Ruchirawat, S.; Prachyawarakorn, V. Cytotoxic and Cancer Chemopreventive Properties of Prenylated Stilbenoids from Macaranga siamensis. Tetrahedron 2015, 71, 5562-5571.
5. Pailee, P.; Prachyawarakorn, V.; Ruchirawat, S.; Mahidol, C. Bioactive Cardinane Sesquiterpenes from the Stems of Alangium salviifolium. Chem. Asian J. 2015, 10, 910-914.
6. Pailee, P.; Prachyawarakorn, V.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Protoberberine Alkaloids and Cancer Chemopreventive Properties of Compounds from Alangium salviifolium. Eur. J. Org. Chem. 2011, 20-21, 3809-3814.

Other Publications

1. Pailee, P.; Ploypradith, P.; Mahidol, C.; Ruchirawat, S.; Prachyawarakorn, V. Dulcisenes C-E; Polyoxygenated Cyclohexenes; from Uvaria dulcis dunal and Their Cytotoxic Activity. Phytochemistry 2022, 202, 113298.
2. Lelakova, V.; Beraud-Dufour, S.; Hosek, J.; Smejkal, K.; Prachyawarakorn, V.; Pailee, P.; Widmann, C.; Vaclavik, J.; Coppola, T.; Mazella, J.; Blondeau, N.; Heurteaux, C. Therapeutic Potential of Prenylated Stilbenoid Macasiamenene F through Its Anti-inflammatory and Cytoprotective Effects on LPS-challenged Monocytes and Microglia. J. Ethnopharmacol. 2020, 263, 113147.
3. Hosek, J.; Lelakova, V.; Bobal, P.; Pizova, H.; Gazdova, M.; Malanik, M.; Jakubczyk, K.; Vesely, O.; Landa, P.; Lelakova, V.; Schuster, D.; Prachyawarakorn, V.; Pailee, P.; Ren, G.; Zpurny, F.; Oravec, M.; Smejkal, K. Prenylated Stilbenoids Affect Inflammation by Inhibiting the NF-κB/AP-1 Signaling Pathway and Cyclooxygenases and Lipoxygenase. J. Nat. Prod. 2019, 82, 1839-1848.
4. Jaipetch, T.; Hongthong, S.; Kuhakarn, C.; Pailee, P.; Piyachaturawat, P.; Suksen, K.; Kongsaeree, P.; Prabpai, S.; Nuntasaen, N.; Reutrakul, V. Cytotoxic Polyoxygenated Cyclohexene Derivatives from the Aerial Parts of Uvaria cherrevensis. Fitoterapia 2019, 137, 104182.
5. Pailee, P.; Kuhakarn, C.; Sangsuwan, C.; Hongthong, S.; Piyachaturawat, P.; Suksen, K.; Jariyawat, S.; Akkarawongsapat, R.; Limthongkul, J.; Napaswad, C.; Kongsaeree, P.; Prabpai, S.; Jaipetch, T.; Pohmakotr, M.; Tuchinda, P.; Reutrakul, V. Anti-HIV and Cytotoxic Biphenyls, Benzophenones and Xanthones from Stems, Leaves and Twigs of Garcinia speciosa. Phytochemistry 2018, 147, 68-79.
6. Pailee, P.; Kruahong, T.;  Hongthong, S.; Kuhakarn, C.; Jaipetch, T.; Pohmakotr, M.; Jariyawat, S.; Suksen, K.; Akkarawongsapat, R.; Limthongkul, J.; Panthong, A.; Kongsaeree, P.; Prabpai, S.; Tuchinda, P.; Reutrakul, V. Cytotoxic, Anti-HIV–1 and Anti-inflammatory Activities of Lanostanes from Fruits of Garcinia speciosa. Phytochem. Lett. 2017, 20, 111-118.
7. Hongthong, S.; Meesin, J.; Pailee, P.; Soorukram, D.; Kongsaeree, P.; Prabpai, S.; Piyachaturawat, P.; Jariyawat, S.; Suksen, K.; Jaipetch, T.; Nuntasaen, N.; Reutrakul, V.; Kuhakarn, C. Cytotoxic Lanostanes from Fruits of Garcinia wallichii Choisy (Guttiferae). Bioorg. Med. Chem. Lett. 2016, 26, 5773-5779.
8. Mahidol, C.; Kittakoop, P.; Prachyawarakorn, V.; Pailee, P.; Prawat, H.; Ruchirawat, S. Recent Investigations of Bioactive Natural Products from Endophytic; Marine-derived; Insect Pathogenic Fungi and Thai Medicinal Plants. Pure Appl. Chem. 2014, 86, 979-993.
9. Rukachaisirikul, V.; Pailee, P.; Hiranrat, A.; Tuchinda, P.; Yoosook, C.; Kasisit, J.; Taylor, W. C.; Reutrakul, V. Anti-HIV-1 Protostane Triterpenes and Digeranylbenzophenone from Trunk Bark and Stems of Garcinia speciosa. Planta Med. 2003, 69, 1141-1146.