Dr. Tawit Suriyo

Name: Dr. Tawit Suriyo

Office address: Laboratory of Pharmacology, 4 ^th Floor, Biomedical Science Building
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +66 2553 8555 (ext. 3159)
E-mail: 

Position: Research Scientist

Research Interests
• Metals (i.e. mercury, cadmium, arsenic) and pesticides (i.e. paraquat, glyphosate, chlopyrifos) toxicity including immunotoxicity, cardiovascular toxicity, and carcinogenicity
• Pharmacology and toxicology of natural products
• Neuronal and non-neuronal cholinergic system

Education
2009-2010 Post-doctoral Fellow, Center of Excellence on Environmental Health and Toxicology, Commission of Higher Education, Ministry of Education, Thailand
2003-2008 Ph.D. (Environmental Engineering and Management; Environmental Toxicology, Technology and Management), Inter-university program between Asian Institute of Technology (AIT)/ Chulabhorn Research Institute (CRI) and Mahidol University (MU), Thailand
1999-2001 M.Sc. (Toxicology), Mahidol University, Thailand
1995-1998 B.Sc. (Industrial Hygiene and Safety), Burapha University, Thailand

Area of expertise
• In vitro and in vivo studies
• Cell cycle and cell signaling
• Flow cytometry-based assay
• Gene expression assay
• Intracellular calcium assay

Award
2015

• SOT/AstraZeneca/SOT Endowment Fund / IUTOX Travel Award, International Union of Toxicology (IUTOX) and US Society of Toxicology (SOT), San Diago, USA. “Suriyo T, Tachachartvanich P, Watcharasit, Satayavivad J. Chlorpyrifos promotes the growth of colorectal adenocarcinoma H508 cells through the activation of EGFR/ERK1/2 signaling pathway”
• ImmunoTools Special Award, ImmunoTools GmbH Company, Germany. “Suriyo T. The immune stimulation and anti-inflammation properties of Thai medicinal plants for the treatment of inflammation-associated cancer”2001
• Good Poster Award on The 27th Congress on Science and Technology of Thailand. Prince of Songkla, Hat Yai, Thailand. “ Suriyo T, Tuntawiroon J, Soontararuk S, Satayavivad J. Modification of rotational behavior during subchronic exposure to paraquat in rat”.

Publications

• Variation of nicotinic subtype α7 and muscarinic subtype M3 acetylcholine receptor expression in three main types of leukemia
  Suriyo T, Chotirat S, Auewarakul CU, Chaiyot K, Promsuwicha O, Satayavivad J.
  Oncol Lett. 2019; 17:1357-1362.
• Sodium arsenite exposure impairs B cell proliferation and enhances vascular inflammation in Plasmodium berghei mouse model
  Suntararuks S, Worasuttayangkurn L, Akanimanee J, Suriyo T, Nookabkaew S, ,Srisamut N, Visitnonthachai D, Watcharasit P, Satayavivad J.
  Environ Toxicol Pharm. 2019; 66: 7-13.
• Potential candidate treatment agents for targeting of cholangiocarcinoma identified by gene expression profile analysis
  Chujan S, Suriyo T, Ungtrakul T, Pomyen Y, Satayavivad J.
  Biomed Rep. 2018, 9: 42-52.
• Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells via non-genomic estrogen receptor/ERK1/2 signaling pathway
  Sritana N, Suriyo T, Kanitwithayanun J, Songvasin BH, Thiantanawat A, Satayavivad J.
  Food Chem Toxicol. 2018; 118: 595-607.
• Arsenic speciation and accumulation in selected organs after oral administration of rice extracts in Wistar rats.
  Lewchalermvong K,Rangkadilok N, Nookabkaew S, Suriyo T, Satayavivad J.
  J Agric Food Chem. 2018, 66: 3199-3209.
• An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity.
  Tajai P, Fedeles BI, Suriyo T, Navasumrit P, Kanitwithayanun J, Essigmann JM, Satayavivad J.
  Free Radic Biol Med. 2018;116: 64-72.
• Clinical parameters following multiple oral dose administration of a standardized Andrographis paniculata capsule in healthy Thai subjects.
  Suriyo T, Pholphana N, Ungtrakul T, Rangkadilok N, Panomvana D, Thiantanawat A, Pongpun W, Satayavivad J.
  Planta Med. 2017;83: 778–789.
• Hijiki and sodium arsenic stimulate growth of human colorectal adenocarcinoma cells through ERK1/2 activation.
  Cholpraipimorat W, Suriyo T, Rangkadilok N, Nookabkaew S, Satayavivad J.
  Food Chem Toxicol 2017; 110: 33-41.
• Andrographis paniculata Diterpenoids protect against radiation-induced transformation in BALB/3T3 cells.
  Nantajit D, Jetawattana S, Suriyo T, Grdina DJ, Satayavivad J.
  Radiat Res. 2017; 188: 66-74
• Andrographis paniculata: dissolution investigation and pharmacokinetic studies of four major active diterpeniods after multiple oral dose.
  Pholphana N, Panomvana D, Rangkadilok N, Suriyo T, Puranajoti P, Ungtrakul T, Pongpun W, Thaeopattha S, Songvut P, Satayavivad J.
  J Ethnopharmacol 194 p513-21 (2016)
• Longan (Dimocarpus longan Lour.) inhibits liposaccharide-stimulated nitric oxide production in macrophages by suppressing NF-B and AP-1 signaling pathways.
  Kunworarah N, Rankadilok N, Suriyo T, Thiantanawat A, Satayavivad J.
  J Ethnopharmacol 179 p156-61 (2016)
• Cholinergic activation enhances retinoic acid-induced differentiation in the human NB-4 acute promyelocytic leukemia cell line.
  Chotirat S, Suriyo T, Hokland M, Hokland P, Satayavivad J, Auewarakul CU.
  Blood Cells Mol Dis 59 p77-84 2016
• A simple and sensitive LC-MS/MS method for determination of four major active diterpenoids from Andrographis paniculata in human plasma and its application to a pilot study.
  Pholphana N, Panomvana D, Rangkadilok N, Suriyo T, Ungtrakul T, Pongpun W, Thaeopattha S, Satayavivad J.
  Planta Med 82 p113-20 (2016)
• Perfluorinated chemicals, PFOS and PFOA, enhance the estrogenic effects of 17 β –estradiol in T47D human breast cancer cells.
  Sonthithai P, Suriyo T, Thiantanawat A, Watcharasit P, Ruchirawat M, Satayavivad J.
  J Applied Toxicol 36 p790-801 (2016)
• Chlorpyrifos promotes colorectal adenocarcinoma H508 cell growth through the activation of EGFR/ERK1/2 signaling pathway but not cholinergic pathway.
  Suriyo T, Tachachartvanich P, Visitnonthachai D, Watcharasit P, Satayavivad J.
  Toxicology. 338: 117-29.(2015)
• Taurolithocholic acid promotes intrahepatic cholangiocarcinoma cell growth via muscarinic acetylcholine receptor and EGFR/ERK1/2 signaling pathway.
  Amonyingcharoen S, Suriyo T, Watcharasit P, Thiantanawat A, and Satayavivad J.
  International Journal of Oncology, in press. DOI: 10.3892/ijo.2015.2939
• Arsenic, cadmium, and manganese levels in shellfish from Map Ta Phut, an industrial area in Thailand, and the potential toxic effects on human cells.
  Rangkadilok N, Siripriwon P, Nookabkaew S, Suriyo T, and Satayavivad J.
  Archives of Environmental Contamination and Toxicology, 2015, 68:169-180. DOI: 10.1007/s00244-014-0054-2
• Andrographis paniculata extracts and major constituent diterpenoids inhibit growth of intrahepatic cholangiocarcinoma cells by inducing cell cycle arrest and apoptosis.
  Suriyo T, Pholphana N,Rangkadilok N, Thiantanawat A,  Watcharasit P, and Satayavivad J.
  Planta Medica, 2014 May; 80 (7):533-543.          DOI: 10.1055/s-0034-1368399
• Glyphosate induces human breast cancer cells growth via estrogen receptors.
  Thongprakaisang S, Thiantanawat A, Rangkadilok N, Suriyo T, and Satayavivad J.
  Food and Chemical Toxicology, 2013 Sep; 59:129-36.    DOI: 10.1016/j.fct.2013.05.057
• Arsenite promotes apoptosis and dysfunction in microvascular endothelial cells via an alteration of intracellular calcium homeostasis.
  Suriyo T, Watcharasit P, Thiantanawat A, and Satayavivad J.
  Toxicology in vitro, 2012 26(3), 386-395. DOI: 10.1016/j.tiv.2011.12.017
• Effects of paraoxon on neuronal and lymphocytic cholinergic system.
  Charoenying T, Suriyo T, Thiantanawat A, Chaiyaroj SC, Parkpian P, and Satayavivad J.
  Environmental Toxicology and Pharmacology, 2011 31(1), 119-128. DOI: 10.1016/j.etap.2010.09.012
• Arsenic and Immune System: The Involvement of Cholinergic Lymphatic Receptors.
  Satayavivad J, and Suriyo T.
  Drug Metabolism Reviews, 2009; 41 (Suppl.2), 11-12.
• Involvement of the lymphocytic muscarinic acetylcholine receptor in methylmercury-induced c-Fos expression and apoptosis in human leukemic T cells.
  Suriyo T, Thiantanawat A,  Chaiyaroj SC,  Parkpian P, and Satayavivad J.
  Journal of Toxicology and Environmental Health: Part A, 2008; 71(16), 1109 – 1123. DOI: 10.1080/15287390802114725
• The effect of repeated low dose exposure to methylmercury on the immunological profiles and lymphocytic muscarinic acetylcholine receptor in mice model.
  Suriyo T, Thiantanawat A, Watcharasit P, and  Satayavivad J. 
  Toxicology Letters, 2008 180 (Suppl.1), S217.  DOI: 10.1016/j.toxlet.2008.06.14