Ms. Khajeelak Chiablaem
Name: Miss Khajeelak Chiablaem
Office address: Research Laboratory of Biochemistry, Chulabhorn Research Institute,
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +662-5538555 (ext. 3238)
E-mail: [email protected]
Positions: Research Scientist, Research Laboratory of Biochemistry, Chulabhorn Research Institute
Research Interests
1. Cancer bioinformatics
2. Cancer invasion and metastasis
3. Cancer and alternative medicine
Education and Degrees:
• B.Sc. (Biology), Chiang Mai University, Thailand
• M.Sc. (Technoprenership and Innovation Management), Chulalongkorn University, Thailand
• Ph.D. Candidate (Translational Medicine), Mahidol University, Thailand
ORCID ID: http://orcid.org/0000-0002-9139-4695
Publications
1. Shiao MS, Chiablaem K, Charoensawan V, Ngamphaiboon N, Jinawath N. Emergence of Intrahepatic
Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer
Type. Front Genet. 2018 Aug 15;9:309. doi: 10.3389/fgene.2018.00309. PMID: 30158952; PMCID:
PMC6104394.
2. Samutprasert P, Chiablaem K, Teeraseranee C, Phaiyarin P, Pukfukdee P, Pienpinijtham P, Svasti J, Palaga T, Lirdprapamongkol K, Wanichwecharungruang S. Epigallocatechin gallate-zinc oxide co-crystalline nanoparticles as an anticancer drug that is non-toxic to normal cells. RSC Adv. 2018 Feb 15;8(14):7369-7376. doi: 10.1039/c7ra10997k. PMID: 35539101; PMCID: PMC9078484.
3. Kuljittichanok D, Diskul-Na-Ayudthaya P, Weeraphan C, Chokchaichamnankit D, Chiablaem K,
Lirdprapamongkol K, Svasti J, Srisomsap C. Effect of Derris scandens extract on a human hepatocellular
carcinoma cell line. Oncol Lett. 2018 Aug;16(2):1943-1952. doi: 10.3892/ol.2018.8824. Epub 2018 May
29. PMID: 30034552; PMCID: PMC6053636.
4. Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Keeratichamroen S, Ngiwsara L,
Paricharttanakul NM, Lirdprapamongkol K, Weeraphan C, Svasti J, Srisomsap C. Apigenin inhibits
growth and induces apoptosis in human cholangiocarcinoma cells. Oncol Lett. 2017 Oct;14(4):4361-
4371. doi: 10.3892/ol.2017.6705. Epub 2017 Aug 2. PMID: 28943950; PMCID: PMC5604180.
5. Seemork J, Sansureerungsikul T, Sathornsantikun K, Sinthusake T, Shigyou K, Tree-Udom T,
Jiangchareon B, Chiablaem K, Lirdprapamongkol K, Svasti J, Hamada T, Palaga T,
Wanichwecharungruang S. Penetration of Oxidized Carbon Nanospheres through Lipid Bilayer
Membrane: Comparison to Graphene Oxide and Oxidized Carbon Nanotubes, and Effects of pH and
Membrane Composition. ACS Appl Mater Interfaces. 2016 Sep 14;8(36):23549-57. doi:
10.1021/acsami.6b07908. Epub 2016 Sep 1. PMID: 27404585.
6. Chiablaem K, Lirdprapamongkol K, Keeratichamroen S, Surarit R, Svasti J. Curcumin suppresses
vasculogenic mimicry capacity of hepatocellular carcinoma cells through STAT3 and PI3K/AKT inhibition.
Anticancer Res. 2014 Apr;34(4):1857-64. PMID: 24692720.
7. Amornwachirabodee K, Chiablaem K, Wacharasindhu S, Lirdprapamongkol K, Svasti J,
Vchirawongkwin V, Wanichwecharungruang SP. Paclitaxel delivery using carrier made from curcumin
derivative: synergism between carrier and the loaded drug for effective cancer treatment. J Pharm Sci.
2012 Oct;101(10):3779-86. doi: 10.1002/jps.23263. Epub 2012 Jul 17. PMID: 22806358.
8. Weeraphan C, Diskul-Na-Ayudthaya P, Chiablaem K, Khongmanee A, Chokchaichamnankit D,
Subhasitanont P, Svasti J, Srisomsap C. Effective enrichment of cholangiocarcinoma secretomes using
the hollow fiber bioreactor culture system. Talanta. 2012 Sep 15;99:294-301. doi:
10.1016/j.talanta.2012.05.054. Epub 2012 Jun 16. PMID: 22967555.
9. Lirdprapamongkol K, Chiablaem K, Sila-Asna M, Surarit R, Bunyaratvej A, Svasti J. Exploring stemness
gene expression and vasculogenic mimicry capacity in well- and poorly-differentiated hepatocellular
carcinoma cell lines. Biochem Biophys Res Commun. 2012 Jun 8;422(3):429-35. doi:
10.1016/j.bbrc.2012.05.009. Epub 2012 May 9. PMID: 22580004.
10. Thetsrimuang C, Khammuang S, Chiablaem K, Srisomsap C, Sarnthima R. Antioxidant properties and
cytotoxicity of crude polysaccharides from Lentinus polychrous Lév. Food Chem 2011; 128(3): 634-639.
11. Suwannateep N, Banlunara W, Wanichwecharungruang SP, Chiablaem K, Lirdprapamongkol K, Svasti
J. Mucoadhesive curcumin nanospheres: biological activity, adhesion to stomach mucosa and release of
curcumin into the circulation. J Control Release. 2011 Apr 30;151(2):176-82. doi:
10.1016/j.jconrel.2011.01.011. Epub 2011 Jan 15. PMID: 21241751.
12. Pruksakorn D, Lirdprapamongkol K, Chokchaichamnankit D, Subhasitanont P, Chiablaem K, Svasti J,
Srisomsap C. Metabolic alteration of HepG2 in scaffold-based 3-D culture: proteomic approach.
Proteomics. 2010 Nov;10(21):3896-904. doi: 10.1002/pmic.201000137. PMID: 20925055.
13. Srisomsap C, Sawangareetrakul P, Subhasitanont P, Chokchaichamnankit D, Chiablaem K,
Bhudhisawasdi V, Wongkham S, Svasti J. Proteomic studies of cholangiocarcinoma and hepatocellular
carcinoma cell secretomes. J Biomed Biotechnol 2010; Article ID 437143, 18 pages.
14. Srisomsap C, Sawangareetrakul P, Subhasitanont P, Chokchaichamnankit D, Chiablaem K,
Bhudhisawasdi V, Wongkham S, Svasti J. Proteomic studies of cholangiocarcinoma and hepatocellular
carcinoma cell secretomes. J Biomed Biotechnol. 2010; 2010:437143. doi: 10.1155/2010/437143. Epub
2009 Dec 27. PMID: 20069059; PMCID: PMC2801507.
15. Rubporn A, Srisomsap C, Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Svasti J, Sangvanich
P. Comparative proteomic analysis of lung cancer cell line and lung fibroblast cell line. Cancer Genomics
Proteomics. 2009 Jul-Aug;6(4):229-37. PMID: 19657000.
16. Srisomsap C, Subhasitanont P, Sawangareetrakul P, Chokchaichamnankit D, Chiablaem K, and Svasti
J. Identification of Potential Biomarkers to Differentiate Human Cholangiocarcinoma and Hepatocellular
Carcinoma from Cell Lines. Anticancer Research 2008; 28: 3495-3496.
17. Srisomsap C, Subhasitanont P, Sawangareetrakul P, Chokchaichamnankit D, Ngiwsara L, Chiablaem K,
Svasti J. Comparison of membrane-associated proteins in human cholangiocarcinoma and
hepatocellular carcinoma cell lines. Proteomics Clin Appl. 2007 Jan;1(1):89-106. doi:
10.1002/prca.200600168. Epub 2006 Dec 5. PMID: 21136613.
