Dr. Pennapa Thongararm

Name: Dr. Pennapa Thongararm, Ph.D.

Office address: Research Laboratory of Environmental Toxicology, Chulabhorn Research Institute,
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +662-553-8555 ext. 3202 (office), +6699-982-9653 (mobile)
Positions: Research Scientist, Research Laboratory of Environmental Toxicology, Chulabhorn Research Institute
E-mail: [email protected]

Research Interests

1. Establishment of a Single-Cell Model as Rapid Screening and a Versatile Tool for High-throughput Toxicological and Mutational Analysis
2. Modulation of Mutational Signatures of Environmental Carcinogens by DNA Repairs Deficiency and Chemoprevention
3. Action-triggering Biomarkers of Exposure to Environmental Carcinogens

Education and Degrees:

• B.S.(Hons) Biology, Kasetsart University, Bangkok, Thailand, 2010-2014
• Ph.D. in Applied Biological Sciences (Environmental Health), Chulabhorn Graduate Institute, Bangkok, Thailand, 2014-2019

Academic Positions

• Postdoctoral Fellow in Molecular Biotechnology and Sciences for the Health, University of Torino, Torino, Italy, 2021-2022
• Postdoctoral Associate in Biological Engineering, Massachusetts Institute of Technology, Cambridge, U.S.A, 2019-2020
• Visiting Graduate Student in Biological Engineering, Massachusetts Institute of Technology, Cambridge, U.S.A, 2017-2018

Academic Activities

International Activities

• Speaker and Modulator at World Congress on Cancer Research & Therapy, Rome, Italy, 2019
  “Dynamic mutational spectra of UVC-induced DNA damage formation and mutagenesis in gpt delta mouse embryonic fibroblast cell line under the conductions of conventional selected and high-resolution unselected mutational strategies”

Local Activities

• Speaker at the 9^th Conference on Science and Technology for Youths, Bangkok, Thailand, 2014
  “Cytotoxicity of snail mucus proteins inducing cell death in breast cancer cell line”

• Speaker at the 6^th International Kasetsart University Science and Technology Annual Research Symposium, Bangkok, Thailand, 2014
  “Cytotoxicity of Achatina fulica mucus fractions inducing cell death in MCF-7 human breast cancer cell line”

Professional Societies

• Member: Superfund Research Program (SRP), Massachusetts Institute of Technology, U.S.A., 2019-2020 

Fellowships

• Research Scholarships of the University of Torino, 2021
• Royal Government of Thailand Scholarship, Development and Promotion of Science and Technology Talents Project (DPST), 2010-2019

Local Awards & Honours

• Outstanding Thesis Defense in Doctor of Philosophy in Applied Biological Sciences, Chulabhorn Graduate Institute, Bangkok, Thailand, 2019
• Outstanding Award for Graduation with the highest GPAX in Science Course and Obtained a GPAX of 3.50 or Above, The Professor Dr. Tab Nilanidhi Foundation, Bangkok, Thailand, 2014
• First Class Honor in Biology, Bachelor of Science (Gold Medal), Kasetsart University, Bangkok, Thailand, 2014

ORCID iD: https://orcid.org/0000-0001-8071-9290

Publications 

1. Armijo AL*, Thongararm P*, Fedeles BI*, Yau J, Kay, JE, et al. Molecular Origins of Mutational Spectra Produced by the Environmental Carcinogen N-Nitrosodimethylamine and S_N1Chemotherapeutic Agents. NAR Cancer. Forthcoming 2023.
2. Thongararm P*, Fedeles BI, Khumsubdee S, Armijo AL, Kim L, Thiantanawat A, et al. Modulation of N-Methyl-N-Nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O⁶-Methylguanine Methyltransferase, MGMT. Chem Res Toxicol. 2020 Feb 17;33(2):625–33.
3. E-kobon T*, Thongararm P, Roytrakul S, Meesuk L, Chumnanpuen P. Prediction of Anticancer Peptides Against MCF-7 Breast Cancer Cells from the Peptidomes of Achatina fulica Mucus Fractions. Comput Struct Biotechnol J. 2015 Dec 7;14:49–57.