Dr. Phanit Songvut
Name: Dr. Phanit Songvut
Office address:
Laboratory of Pharmacology, 4 th Floor, Biomedical Science Building, 54 Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +66 2553 8555 (ext. 3168)
E-mail: [email protected]
Research Interests
- Preclinical and clinical pharmacokinetics
- Metabolomics
Education
- Doctor of Philosophy, Ph.D. (Pharmacology and Toxicology), Faculty of Pharmacy, Chulalongkorn University
- Bachelor of Pharmacy (B. Pharm.), Faculty of Pharmacy, Chiangmai University
Scholarships
- Research Attachment Program Student (Metabolomics): Institute of System Biology (INBIOSIS), National University of Malaysia, Malaysia
- Overseas Research Experience Scholarship (Daniel K. Inouye of Pharmacy, University of Hawaii Hilo, USA)
- Doctoral Scholarship: The 100th Anniversary Chulalongkorn University for Doctoral Scholarship, Chulalongkorn University, Thailand
- Graduate Student Scholarship: The Celebration on the Auspicious Occasion of Her Royal Highness Princess Maha Chakri Sirindhorn’s Cycle (60th) Birthday, Thailand
- Doctoral Scholarship: The 90th Anniversary Chulalongkorn University Fund (Ratchadaphiseksomphot Endowment Fund)
- IRPUS: Industrial and Research Projects for Undergraduate Students, The Thailand Research Fund (TRF)
Awards
Graduate Research Excellence in Herbal Medicine 2023, Vichiara Jirawongsae Award, Certificate of Excellence in Herbal Medicine, oral presentation and poster presentation, the 38th International Annual Meeting in Pharmaceutical Sciences
“Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers”
Songvut P, Chariyavilaskul P, Khemawoot P, Tansawat R
The excellent poster presentation award (Herbal and complementary medicine innovation) at the 41st Pharmacological and Therapeutic Society of Thailand Meeting
“Interspecies Differences in Pharmacokinetic and Metabolic Profiles of Triterpenoid Glycosides in Standardized Extract of Centella asiatica, ECa 233”
Songvut P, Anukunwithaya T, Chariyavilaskul P, Tantisira M.H., Khemawoot P.
The best poster presentation award (Animal Research) Pharmacological and Therapeutic Society of Thailand Meeting
“Pharmacoenhancing Effects of Piperine on Disposition Kinetics of Oxyresveratrol in Rats”
Junsaeng D, Anukunwithaya T, Songvut P, Sritularak B, Likhitwitayawuid K, Khemawoot P.
Publications
1.Unraveling the interconversion pharmacokinetics and oral bioavailability of the major ginger constituents: [6]-gingerol, [6]-shogaol, and zingerone after single-dose administration in rats.
Songvut P, Nakareangrit W, Cholpraipimolrat W, Kwangjai J, Worasuttayangkurn L, Watcharasit P, & Satayavivad J.
Front Pharmacol, 2024; 15, 1391019.
Doi: 10.3389/fphar.2024.1391019
2.Comparison of diterpenoid contents and dissolution profiles of selected Andrographis paniculata crude and extract capsules
Rangkadilok N, Pholphana N, Akanimanee J, Panomvana D, Puranajoti P, Songvut P, Satayavivad J.
Phytochem Anal, 2024.
Doi: 10.1002/pca.3364
3.Enhancing oral bioavailability of andrographolide using solubilizing agents and bioenhancer: comparative pharmacokinetics of Andrographis paniculata formulations in beagle dogs
Songvut P, Boonyarattanasoonthorn T, Nuengchamnong N, Junsai T, Kongratanapasert T, Supannapan K, Khemawoot P.
Pharm Biol. 2024; 62(1): 183-194.
Doi: 10.1080/13880209.2024.2311201
4.Untargeted metabolomics reveal pathways associated with neuroprotective effect of oxyresveratrol in SH-SY5Y cells
Mahamud N, Songvut P, Muangnoi C, Rodsiri R, Dahlan W, & Tansawat R.
Sci Rep. 2023; 13(1): 20385.
Doi: 10.1038/s41598-023-47558-y
5.Comparative pharmacokinetics and safety evaluation of high dosage regimens of Andrographis paniculata aqueous extract after single and multiple oral administration in healthy participants
Songvut P, Rangkadilok N, Pholphalna N, Suriyo T, Panomvana D, Puranajoti P, et al.
Front Pharmacol. 2023; 14.
Doi: 10.3389/fphar.2023.1230401
6.A validated LC-MS/MS method for clinical pharmacokinetics and presumptive phase II metabolic pathways following oral administration of Andrographis paniculata extract.
Songvut P, Pholphalna N, Suriyo T, Rangkadilok N, Panomvana D, Puranajoti P, et al.
Sci Rep. 2023; 13(1): 2534.
Doi: https://doi.org/10.1038/s41598-023-28612-1
7.A comprehensive review on disposition kinetics and dosage of oral administration of Andrographis paniculata, an alternative herbal medicine, in co-treatment of coronavirus disease.
Songvut P, Suriyo T, Panomvana D, Rangkadilok N, Satayavivad J.
Front Pharmacol. 2022; 13.
Doi: 10.3389/fphar.2022.952660
8.Increase water solubility of Centella asiatica extract by indigenous bioenhancers could improve oral bioavailability and disposition kinetics of triterpenoid glycosides in beagle dogs.
Boonyarattanasoonthorn T, Kijtawornrat A, Songvut P, Nuengchamnong N, Buranasudja V, Khemawoot P.
Sci Rep. 2022; 12(1): 1-11.
Doi: https://doi.org/10.1038/s41598-022-06967-1
9.Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers.
Songvut P, Chariyavilaskul P, Khemawoot P, Tansawat R.
Sci Rep. 2021; 11(1): 1-13.
Doi: https://doi.org/10.1038/s41598-021-86267-2
10.Comparative pharmacokinetics of puerarin alone and in Pueraria miriflca extract in female cynomolgus monkeys.
Namken S, Songvut P, Nuengchamnong N, Kemthong T, Khemawoot P, Malaivijitnond S.
Planta Med. 2021; 87(05): 395-403.
Doi: https://doi.org/10.1055/a-1271-7092
11.Safety and pharmacokinetics of standardized extract of Centella asiatica (ECa 233) capsules in healthy Thai volunteers: A Phase l Clinical Study.
Songvut P, Chariyavilaskul P, Tantisira M.H., Khemawoot P.
Planta med. 2019; 85(06). 483-490.
Doi: https://doi.org/10.1055/a-0835-6671
12.Inverted U-shaped response of a standardized extract of Centella asiatica (ECa 233) on memory enhancement.
Boondam Y, Songvut P, Tantisira M.H, Tapechum S, Tilokskulchai K, Pakaprot N.
Sci Rep. 2019; 9(1):1-11.
Doi: https://doi.org/10.1038/s41598-019-44867-z
13.Comparative pharmacokinetics of oxyresveratrol alone and in combination with piperine as a bioenhancer in rats.
Junsaeng D, Anukunwithaya T, Songvut P, Sritularak B, Likhitwitayawuid K, Khemawoot P.
BMC Complement Altern Med. 2019; 19 (l):235.
Doi: https://doi.org/10.1186/s12906-019-2653-y
14.Andrographis paniculata : Dissolution investigation and pharmacokinetic studies of four major active diterpenoids after multiple oral dose administration in healthy Thai volunteers.
Pholphalna N, Panomvana D, Rangkadilok N, Suriyo T, Puranajoti P, Songvut P, et al.
J Ethnopharmacol 2016; 194: 513-521.
Doi: https://doi.org/10.1016/j.jep.2016.09.058
15.The development of antipyretics gel from Thai medicinal plants.
Chaiwan A, Leelapornpisit P, Phaosri M, Pitiporn S, Songvut P, Vejabhikul S.
J Thai Trad Alt Med. 2010; 8(2):41.
