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Medicinal Chemistry

Medicinal Chemistry

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A structure-based virtual high-throughput screening, molecular docking, molecular dynamics and MM/PBSA study identified novel putative drug-like dual inhibitors of trypanosomal cruzain and rhodesain cysteine proteases

Eurtivong C, Zimmer C, Schirmeister T, Butkinaree C, Saruengkhanphasit R, Niwetmarin W, Ruchirawat S, Bhambra AS

Mol Drivers. 2024;28(2):531-51.

Visible light-induced one-pot carbonylation of alkyl halides with aryl formates

Chuentragool P, Ngamnithiporn A, Hongboon P, Ruchirawat S

J Org Chem. 2024;89(6):4205-4209.

Dihydro-10H-indeno[1,2-b]benzofurans and Tetrahydroindeno[1,2-c]isochromenes via stereoselective intramolecular carbocation cascade cyclization

Tangdenpaisal K, Kheakwanwong W, Ruchirawat S, Ploypradith P

J Org Chem. 2024;89(5):2964-2983.

Molecular reconstruction with stereochemical relay: An investigation into the rearrangement of spiro[4.5]decadienone to benzoxepane

Sittihan S, Harada S, Isono T, Nemoto T, Ruchirawat S

Chem Asian J. 2024;19:e202300937.

Controllable chemoselectivity cascade reactions for the synthesis of phenanthrenols via Palladium-Catalyzed-Suzuki/Heck Reaction and Michael Addition

Yongpanich P, Chatrangsan K, Tummatorn J, Thongsornkleeb C, Ruchirawat S

Chem Asian J. 2024.

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