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Medicinal Chemistry

Medicinal Chemistry

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Disadee, W.; Ruchirawat, S. Oxazaborolidine-Catalyzed Reductive Parallel Kinetic Resolution of Ketones from β-Nitro-Azabicycles for the Synthesis of Chiral Hypoestestatins 1, 2. Org. Biomol. Chem. 2021, 19, 8794–8805.

Reamtong, O.; Lapmanee, S.; Tummatorn, J.; Palavong, N.; Thongsornkleeb, C.; Ruchirawat, S. Synthesis of Benzoazepine Derivatives via Azide Rearrangement and Evaluation of Their Antianxiety Activities. ACS Med. Chem. Lett. 2021, 12, 1449–1458.

Anukanon, S.; Pongpamorn, P.; Tiyabhorn, W.; Chatwichien, J.; Niwetmarin, W.; Sessions, R. B.; Ruchirawat, S.; Thasana, N. In silico-guided Rational Drug Design and Semi-synthesis of C(2) Functionalized Huperzine A Derivatives as Acetylcholinesterase Inhibitor. ACS Omega 2021, 6, 19924–19939.

Jaithum, K.; Tummatorn, J.; Boekfa, B.; Thongsornkleeb, C.; Chainok, K.; Ruchirawat, S. Diastereoselective Synthesis of Spirocyclic Ether from ortho-Carbonylarylacetylenols via Silver-Catalyzed Cyclization under Acidic Conditions. Adv. Synth. Catal. 2021, 363, 3812–3834.

Thongsornkleeb, C.; Tummatorn, J.; Ruchirawat, S. Utilization of ortho-alkynylarylcarbonyl derivatives for creating structurally diverse chemical compounds. Org. Biomol. Chem. 2021, 19, 5982–5998.

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