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Medicinal Chemistry

Medicinal Chemistry

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Ieawsuwan, W.; Pingaew, R.; Kunkaewom, S.; Ploypradith, P.; Ruchirawat, S. Scandium(III) Triflate-Catalyzed Pinacol-Pinacolone Rearrangement and Cyclization of 1,2-Diaryl-1,2-ethanediol: The Versatile Synthesis of 1-Aryl-2,3-dihydro-1H-3-benzazepines. Asian J. Org. Chem. 2019, 8, 1441–1447.

Ruengsangtongkul, S.; Chaisan, N.; Thongsornkleeb, C.; Tummatorn, J.; Ruchirawat, S. Rate Enhancement in CAN-Promoted Pd(PPh3)2Cl2-Catalyzed Oxidative Cyclization: Synthesis of 2-Ketofuran-4-carboxylate Esters. Org. Lett. 2019, 21, 2514–2517.

Tummatorn, J.; Punjajom, K.; Rodphon, W.; Ruengsangtongkul, S.; Chaisan, N.; Lumyong, K.; Thongsornkleeb, C.; Nimnual, P.; Ruchirawat, S. Chemoselective Synthesis of 1,1-Disubstituted Vinyl Triflates from Terminal Alkynes Using TfOH in the Presence of TMSN3. Org. Lett. 2019, 21, 4694–4697.

Lekky, A.; Ruengsatra, T.; Ruchirawat, S.; Ploypradith, P. Stereoselective Convergent Synthesis of Tetrahydro-5H-benzo[c]fluorene via Nine-Membered Ring-Closing Metathesis and Transannular Acid-Mediated Cyclization/Nucleophilic Addition. J. Org. Chem. 2019, 84, 5277–5291.

Nimnual, P.; Tummatorn, J.; Boekfa, B.; Thongsornkleeb, C.; Ruchirawat, S.; Piyachat, P.; Punjajom, K. Construction of 5-Aminotetrazoles via in Situ Generation of Carbodiimidium Ions from Ketones Promoted by TMSN3/TfOH. J. Org. Chem. 2019, 84, 5603–5613.

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