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Medicinal Chemistry

Medicinal Chemistry

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Disadee, W.; Ruchirawat S. One-pot Cascade Synthesis of Azabicycles via the Nitro-Mannich Reaction and N-Alkylation. Org. Biomol. Chem. 2018, 16, 707–711.

Nimnual, P.; Norseeda, K.; Akkachairin, B.; Tummatorn, J.; Laohapaisan, P.; Supantanapong, N.; Chuangsoongnern, P.; Thongsornkleeb, C.; Sittihan, S.; Ruchirawat, S.; Rodphon, W., Synthesis of β-Naphthols and Naphthofuranones from o-Alkynylarylketones via Sequential AgTFA-Catalyzed Ketonization-Intramolecular Aldol Condensation: Total Synthesis of Negundin A. Asian J. Org. Chem. 2018, 7, 932-945.

Pramthaisong, C.; Worayuthakarn R.; Pharikronburee, V.; Duangthongyou, T.; Rattanakam, R.; Ruchirawat, S.; Thasana, N. Base-Mediated Cascade Cyclization: Stereoselective Synthesis of Benzooxazocinone. Org. Lett. 2018, 20, 4015–4019.

Songthammawat, P.; Wangngae, S.; Matsumoto, K.; Duangkamol, C.; Ruchirawat, S.; Ploypradith, P. Bio-Inspired Diastereoconvergent Synthesis of the Tricyclic Core of Palodesangrens via Diels-Alder Reaction, LiAlH4-Mediated Isomerization, and Acid-Mediated Cyclization. J. Org. Chem. 2018, 83, 5225–5241.

Akkachairin, B.; Tummatorn, J.; Khamsuwan, N.; Thongsornkleeb, C.; Ruchirawat, S. Domino N2-Extrusion-Cyclization of Alkynylarylketone Derivatives for the Synthesis of Indoloquinolines and Carbocycle-Fused Quinolines. J. Org. Chem. 201883, 11254–11268.

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