การศึกษากลไกของการยับยั้งการทำงานของยีนที่เกี่ยวข้องกับการแบ่งเซลล์แบบไมโทซีสในเซลล์มะเร็งท่อน้ำดี

ผลงานตีพิมพ์

2565 – Present

Khatib, S. A., Ma, L., Dang, H., Forgues, M., Chung, J. Y., Ylaya, K., . . . Wang, X. W. (2022). Single-cell biology uncovers apoptotic cell death and its spatial organization as a potential modifier of tumor diversity in HCC. Hepatology, 76(3), 599-611. doi:10.1002/hep.32345

Kheawchaum, S., Mahidol, C., Thongnest, S., Boonsombat, J., Batsomboon, P., Sitthimonchai, S., . . . Prawat, H. (2022). Ent-abietane diterpenoid lactone glycosides and a phenolic glycoside from Phlogacanthus pulcherrimus T. Anderson with cytotoxic and cancer chemopreventive activities. Phytochemistry, 201, 113261. doi:10.1016/j.phytochem.2022.113261

Bhinija, K., Huehne, P. S., Mongkolsuk, S., Sitthimonchai, S., & Satayavivad, J. (2022). A short-chain dehydrogenase/reductase (SDR) detection for the Isoflavone reductase gene in Bulbophyllum and other orchids. South African Journal of Botany, 144, 295-304. doi:https://doi.org/10.1016/j.sajb.2021.08.034

2564

Schaffer, A. A., Dominguez, D. A., Chapman, L. M., Gertz, E. M., Budhu, A., Forgues, M., . . . Wang, X. W. (2021). Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis. BMC Genomics, 22(1), 814. doi:10.1186/s12864-021-08098-9

Pomyen, Y., Budhu, A., Chaisaingmongkol, J., Forgues, M., Dang, H., Ruchirawat, M., . . . Consortium, T.-L. (2021). Tumor metabolism and associated serum metabolites define prognostic subtypes of Asian hepatocellular carcinoma. Sci Rep, 11(1), 12097. doi:10.1038/s41598-021-91560-1

Hung, M. H., Lee, J. S., Ma, C., Diggs, L. P., Heinrich, S., Chang, C. W., . . . Wang, X. W. (2021). Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma. Nat Commun, 12(1), 1455. doi:10.1038/s41467-021-21804-1

Moolmuang, B., & Ruchirawat, M. (2021). The antiproliferative effects of ataxia-telangiectasia mutated and ATM- and Rad3-related inhibitions and their enhancements with the cytotoxicity of DNA damaging agents in cholangiocarcinoma cells. J Pharm Pharmacol, 73(1), 40-51. doi:10.1093/jpp/rgaa050

Lertsuwan, J., Sawasdichai, A., Tasnawijitwong, N., Gaston, K., Jayaraman, P. S., & Satayavivad, J. (2021). Sequence of CX-4945 and Cisplatin Administration Determines the Effectiveness of Drug Combination and Cellular Response in Cholangiocarcinoma Cells In Vitro. Anticancer Res, 41(12), 6155-6167. doi:10.21873/anticanres.15435

2563

Kitchen, P., Lee, K. Y., Clark, D., Lau, N., Lertsuwan, J., Sawasdichai, A., . . . Jayaraman, P. S. (2020). A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition. Cancer Res, 80(4), 757-770. doi:10.1158/0008-5472.CAN-19-0942

2562
Haznadar, M., Diehl, C. M., Parker, A. L., Krausz, K. W., Bowman, E. D., Rabibhadana, S., . . . Harris, C. C. (2019). Urinary Metabolites Diagnostic and Prognostic of Intrahepatic Cholangiocarcinoma. Cancer Epidemiol Biomarkers Prev, 28(10), 1704-1711. doi:10.1158/1055-9965.EPI-19-0453

Kwon, S. M., Budhu, A., Woo, H. G., Chaisaingmongkol, J., Dang, H., Forgues, M., . . . Wang, X. W. (2019). Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer. Sci Rep, 9(1), 16930. doi:10.1038/s41598-019-52578-8

Weigel, C., Chaisaingmongkol, J., Assenov, Y., Kuhmann, C., Winkler, V., Santi, I., . . . Popanda, O. (2019). DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer. Clin Epigenetics, 11(1), 67. doi:10.1186/s13148-019-0666-5

Fako, V., Martin, S. P., Pomyen, Y., Budhu, A., Chaisaingmongkol, J., Franck, S., . . . Wang, X. W. (2019). Gene signature predictive of hepatocellular carcinoma patient response to transarterial chemoembolization. Int J Biol Sci, 15(12), 2654-2663. doi:10.7150/ijbs.39534

2561

Singhirunnusorn, P., Moolmuang, B., Lirdprapamongkol, K., & Ruchirawat, M. (2018). Arsenite exposure potentiates apoptosis-inducing effects of tumor necrosis factor-alpha- through reactive oxygen species. J Toxicol Sci, 43(2), 159-169. doi:10.2131/jts.43.159 

Lertsuwan, J., Lertsuwan, K., Sawasdichai, A., Tasnawijitwong, N., Lee, K. Y., Kitchen, P., . . . Satayavivad, J. (2018). CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism. Cancers (Basel), 10(9). doi:10.3390/cancers10090283

Lertsuwan, K., Nammultriputtar, K., Nanthawuttiphan, S., Phoaubon, S., Lertsuwan, J., Thongbunchoo, J., . . . Charoenphandhu, N. (2018). Ferrous and ferric differentially deteriorate proliferation and differentiation of osteoblast-like UMR-106 cells. Biometals, 31(5), 873-889. doi:10.1007/s10534-018-0130-6

Roeksomtawin, S., Navasumrit, P., Waraprasit, S., Parnlob, V., Sricharunrat, T., Bhudhisawasdi, V., . . . Ruchirawat, M. (2018). Decreased argininosuccinate synthetase expression in Thai patients with cholangiocarcinoma and the effects of ADI-PEG20 treatment in CCA cell lines. Oncol Lett, 16(2), 1529-1538. doi:10.3892/ol.2018.8807

2560

Chaisaingmongkol, J., Budhu, A., Dang, H., Rabibhadana, S., Pupacdi, B., Kwon, S. M., . . . Consortium, T.-L. (2017). Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma. Cancer Cell, 32(1), 57-70 e53. doi:10.1016/j.ccell.2017.05.009 

Prachayasittikul, V., Pingaew, R., Worachartcheewan, A., Sitthimonchai, S., Nantasenamat, C., Prachayasittikul, S., . . . Prachayasittikul, V. (2017). Aromatase inhibitory activity of 1,4-naphthoquinone derivatives and QSAR study. EXCLI J, 16, 714-726. doi:10.17179/excli2017-309

2559

Moolmuang, B., Singhirunnusorn, P., & Ruchirawat, M. (2016). Effects of 5-Aza-2′-Deoxycytidine, Bromodeoxyuridine, Interferons and Hydrogen Peroxide on Cellular Senescence in Cholangiocarcinoma Cells. Asian Pac J Cancer Prev, 17(3), 957-963. doi:10.7314/apjcp.2016.17.3.957 

Scarzello, A. J., Jiang, Q., Back, T., Dang, H., Hodge, D., Hanson, C., . . . Wiltrout, R. H. (2016). LTbetaR signalling preferentially accelerates oncogenic AKT-initiated liver tumours. Gut, 65(10), 1765-1775. doi:10.1136/gutjnl-2014-308810

2556

Phakeovilay, C., Disadee, W., Sahakitpichan, P., Sitthimonchai, S., Kittakoop, P., Ruchirawat, S., & Kanchanapoom, T. (2013). Phenylethanoid and flavone glycosides from Ruellia tuberosa L. J Nat Med, 67(1), 228-233. doi:10.1007/s11418-012-0658-7 

Nealmongkol, P., Tangdenpaisal, K., Sitthimonchai, S., Ruchirawat, S., & Thasana, N. (2013). Cu(I)-mediated lactone formation in subcritical water: a benign synthesis of benzopyranones and urolithins A–C. Tetrahedron, 69(44), 9277-9283. https://doi.org/10.1016/j.tet.2013.08.045 

2555 

Disadee, W., Mahidol, C., Sahakitpichan, P., Sitthimonchai, S., Ruchirawat, S., & Kanchanapoom, T. (2012). Unprecedented furan-2-carbonyl C-glycosides and phenolic diglycosides from Scleropyrum pentandrum. Phytochemistry, 74, 115-122. doi:10.1016/j.phytochem.2011.11.001 

Worawittayanon, P., Ruadreo, J., Disadee, W., Sahakitpichan, P., Sitthimonchai, S., Thasana, N., . . . Kanchanapoom, T. (2012). Iridoid and flavone glycosides from Asystasia gangetica subsp. micrantha and Asystasia salicifolia and their antioxidant activities. Biochemical Systematics and Ecology, 40, 38-42. https://doi.org/10.1016/j.bse.2011.08.016 

2554 

Disadee, W., Mahidol, C., Sahakitpichan, P., Sitthimonchai, S., Ruchirawat, S., & Kanchanapoom, T. (2011). Flavonol 3-O-robinobiosides and 3-O-(2″-O-α-rhamnopyranosyl)-robinobiosides from Sesuvium portulacastrum. Tetrahedron, 67(23), 4221-4226. https://doi.org/10.1016/j.tet.2011.04.041 

2551 

Buthbumrung, N., Mahidol, C., Navasumrit, P., Promvijit, J., Hunsonti, P., Autrup, H., & Ruchirawat, M. (2008). Oxidative DNA damage and influence of genetic polymorphisms among urban and rural schoolchildren exposed to benzene. Chem Biol Interact, 172(3), 185-194. doi:10.1016/j.cbi.2008.01.005 2550 Rangkadilok, N., Sitthimonchai, S., Worasuttayangkurn, L., Mahidol, C., Ruchirawat, M., & Satayavivad, J. (2007). Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract. Food Chem Toxicol, 45(2), 328-336. doi:10.1016/j.fct.2006.08.022 

2547 

Noonpakdee, W., Sitthimonchai, S., Panyim, S., & Lertsiri, S. (2004). Expression of the catalase gene katA in starter culture Lactobacillus plantarum TISTR850 tolerates oxidative stress and reduces lipid oxidation in fermented meat product. Int J Food Microbiol, 95(2), 127-135. doi:10.1016/j.ijfoodmicro.2004.01.020 

2546 

Gerhauser, C., Klimo, K., Heiss, E., Neumann, I., Gamal-Eldeen, A., Knauft, J., . . . Frank, N. (2003). Mechanism-based in vitro screening of potential cancer chemopreventive agents. Mutat Res, 523-524, 163-172. doi:10.1016/s0027-5107(02)00332-9 

2542 

Kengluecha, A., Noonpakdee, W. S., S. Valyasevi, R. Panyim, S. (1999). High level expression of a catalase gene from Lactobacillus sake SR911 in catalasedeficient Lactobacillus sp. TISTR891 and Lactobacillus plantarum TISTR850. Asia Pac. J. Mol. Biol. Biotechnol. , 7(2), 119-126.